De Cristofaro, Raimondo
 Distribuzione geografica
Continente #
EU - Europa 3.800
NA - Nord America 3.577
AS - Asia 990
AF - Africa 27
SA - Sud America 11
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 8
Totale 8.422
Nazione #
US - Stati Uniti d'America 3.556
DE - Germania 1.301
SE - Svezia 799
CN - Cina 557
UA - Ucraina 455
IT - Italia 310
IE - Irlanda 228
FR - Francia 179
SG - Singapore 157
GB - Regno Unito 136
IN - India 129
PL - Polonia 120
FI - Finlandia 98
RU - Federazione Russa 91
TR - Turchia 37
HK - Hong Kong 28
JP - Giappone 20
IR - Iran 19
BE - Belgio 18
CA - Canada 17
NL - Olanda 17
CI - Costa d'Avorio 10
KR - Corea 9
RO - Romania 9
AU - Australia 8
VN - Vietnam 8
CH - Svizzera 7
CZ - Repubblica Ceca 7
EG - Egitto 6
MK - Macedonia 6
BR - Brasile 5
ES - Italia 5
ID - Indonesia 5
EU - Europa 4
ZA - Sudafrica 4
A2 - ???statistics.table.value.countryCode.A2??? 3
AT - Austria 3
IL - Israele 3
IQ - Iraq 3
TN - Tunisia 3
AR - Argentina 2
BD - Bangladesh 2
DZ - Algeria 2
GR - Grecia 2
KW - Kuwait 2
LV - Lettonia 2
NO - Norvegia 2
PR - Porto Rico 2
TH - Thailandia 2
A1 - Anonimo 1
AM - Armenia 1
BO - Bolivia 1
CL - Cile 1
HR - Croazia 1
HU - Ungheria 1
LU - Lussemburgo 1
MO - Macao, regione amministrativa speciale della Cina 1
MU - Mauritius 1
MX - Messico 1
MY - Malesia 1
NZ - Nuova Zelanda 1
OM - Oman 1
PA - Panama 1
PE - Perù 1
PH - Filippine 1
PT - Portogallo 1
QA - Qatar 1
RS - Serbia 1
SA - Arabia Saudita 1
SC - Seychelles 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
VE - Venezuela 1
Totale 8.422
Città #
Chandler 657
Ashburn 340
Jacksonville 248
Dublin 220
San Mateo 212
Nanjing 157
Wilmington 138
Ann Arbor 112
Warsaw 104
Woodbridge 98
Singapore 95
Dearborn 88
Boston 87
New York 87
Fairfield 77
Moscow 73
Houston 72
Lawrence 71
Redwood City 71
Pune 70
Milan 69
Nürnberg 65
Seattle 58
Beijing 57
Princeton 55
Cattolica 53
Nanchang 52
Marseille 45
Redmond 44
Chicago 38
Izmir 34
Los Angeles 33
University Park 33
Bremen 32
Hangzhou 29
Kunming 27
Mountain View 25
Rome 24
Augusta 23
Hong Kong 22
Norwalk 22
Boardman 21
Changsha 21
Shenyang 21
Detroit 18
Bareggio 17
Hebei 17
Brussels 15
Cambridge 15
Jiaxing 15
Tianjin 15
Zhengzhou 15
Kraków 14
Munich 14
Padova 13
Leawood 12
Shanghai 12
Abidjan 10
Andover 10
Chengdu 10
Hefei 10
Hounslow 10
Lanzhou 10
London 10
Southend 10
Fremont 9
Jinan 9
San Diego 8
Helsinki 7
Lancaster 7
Ardabil 6
Phoenix 6
Prilep 6
Seoul 6
Zurich 6
Busto Arsizio 5
Edinburgh 5
Kish 5
Menlo Park 5
Ningbo 5
Simi Valley 5
Tokyo 5
Washington 5
Brno 4
Dong Ket 4
Falls Church 4
Forest City 4
Guangzhou 4
Gurgaon 4
Hanoi 4
Indiana 4
Millbury 4
Philadelphia 4
San Francisco 4
Sydney 4
Timisoara 4
Amsterdam 3
Camposampiero 3
Castelnuovo Rangone 3
Changchun 3
Totale 4.426
Nome #
Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment 273
Qualitative and quantitative modifications of von willebrand factor in patients with essential thrombocythemia and controlled platelet count 265
The oxidative modification of von Willebrand factor is associated with thrombotic angiopathies in diabetes mellitus. 257
Pathogenesis Of Portal Vein Thrombosis In Liver Cirrhosis: The Role of the ADAMTS13/VWF Unbalance 229
Novel path to IL-6 trans-signaling through thrombin-induced soluble IL-6 receptor release by platelets 148
Thrombotic risk factors in patients with liver cirrhosis: correlation with MELD scoring system and portal vein thrombosis development 128
The Type 2b P.R1306w Natural Mutation Of Von Willebrand Factor Dramatically Enhances The Multimer Sensitivity To Shear Stress 121
Glycaemic variability affects ischaemia-induced angiogenesis in diabetic mice. 120
Prostaglandin E2 differentially modulates human platelet function through the prostanoid EP2 and EP3 receptors 116
Formation of methionine sulfoxide by peroxynitrite at position 1606 of von Willebrand factor inhibits its cleavage by ADAMTS-13. A new prothrombotic mechanism associated with oxidative stress 112
Effect of fibrinogen concentration on the velocity of platelet aggregation. 103
An old drug for a new application: carbazochrome-sodium-sulfonate in HHT 103
Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells 100
Pseudo-acquired vWD in essential thrombocythemia: the role of platelets 98
Evaluation of the thiobarbituric acid test (TBA test) properties for the determination of glycosylated hemoglobins by comparison with chromatography and isoelectrofocusing. 97
The D173G mutation in ADAMTS-13 causes a severe form of congenital thrombotic thrombocytopenic purpura. A clinical, biochemical and in silico study 95
Oxidized von Willebrand factor is efficiently cleaved by serine proteases from primary granules of leukocytes: divergence from adamts-13 94
β2-Glycoprotein I Binds Thrombin and Selectively Inhibits the Enzyme Procoagulant Functions 94
Hyposialylation of neprilysin possibly affects its expression and enzymatic activity in hereditary inclusion-body myopathy muscle 93
Structural and funtional mapping of the thrombin domain involved in the binding to the platelet glycoprotein Ib 86
Kinetic study of von Willebrand factor self-aggregation induced by ristocetin 84
Congenital prothrombin deficiency: an update 81
ORal anticoagulants In fraGile patients with percutAneous endoscopic gastrostoMy and atrIal fibrillation: the (ORIGAMI) study 79
Increased platelet-fibrinogen affinity in patients with myeloproliferative disorders. 78
Presence of portal vein thrombosis in liver cirrhosis is strongly associated with low levels of ADAMTS-13: a pilot study 78
Hexopeptidase high performance liquid chromatography (HPLC) mapping and is application to peptide sequence strategies. 77
PURIFICATION OF THE ISOLATED BETA-CHAIN OF ADULT HUMAN-HEMOGLOBIN FROM ITS POST-TRANSLATIONAL MODIFICATION 76
Defective platelet responsiveness to thrombin and protease-activated receptors agonists in a novel case of gray platelet syndrome: correlation between the platelet defect and the alpha-granule content in the patient and four relatives 75
Aims: The ORal anticoagulants In fraGile patients with percutAneous endoscopic gastrostoMy and atrIal fibrillation (ORIGAMI) study investigates the safety and efficacy of Edoxaban administered via PEG in patients with atrial fibrillation and a clinical indication for a long-term anticoagulation. Design: In this prospective, single-centre observational study, 12 PEG-treated patients with indication to anticoagulation will receive edoxaban via PEG and will be followed up to 6 months. Plasma antifactor Xa activity and edoxaban concentrations will be assessed. Thromboembolic (ischaemic stroke, systemic embolism, venous thromboembolism) and bleeding events (Bleeding Academic Research Consortium and Thrombolysis in Myocardial Infarction) will be recorded at 1 and 6 months. Preliminary results: A retrospective analysis of five atrial fibrillation cases undergoing PEG implantation at our Institution who received edoxaban via PEG showed plasma anti-FXa levels at a steady state of 146 ± 15 ng/ml, without major adverse event at a mean follow-up of 6 months. Conclusion: ORIGAMI prospectively investigates PEG-administration of edoxaban in PEG-treated patients requiring long-term anticoagulation. Our preliminary retrospective data support this route of DOAC administration. 75
high performance liquid chromatography in protein sequence determination. 74
Homocysteinemia is inversely correlated with platelet count and inversely correlated with sE-and sP-selectin levels in females homozygous for C677T methylenetetrahydrofolate reductase 73
Evaluation of assay methods to measure plasma ADAMTS13 activity in thrombotic microangiopathies. 73
Biochemical properties of indoleamine 2,3-dioxygenase: from structure to optimized design of inhibitors 70
On-pump Cardiac Surgery Enhances Platelet Renewal and Impairs Aspirin Pharmacodynamics: Effects of Improved Dosing Regimens 70
Portal vein thrombosis occurrence in a cirrhotic patient during treatment with rivaroxaban 70
Immune toilerance by intermittent factor VIII boluses in two hemophilia A patients 69
Molecular Aggregation of Marketed Recombinant FVIII Products: Biochemical Evidence and Functional Effects 69
Haemostatic system in inflammatory bowel diseases: new players in gut inflammation. 68
The effect of shear stress on protein conformation: Physical forces operating on biochemical systems: The case of von Willebrand factor. 68
Direct oral anticoagulants and therapeutic adherence: do not let your guard down 68
SPONTANEOUS DEEP HEMATOMAS IN 2 PATIENTS WITH MYELOFIBROSIS - EVIDENCE OF PLATELET MEMBRANE GLYCOPROTEIN MODIFICATIONS 67
Allosteric equilibria in the binding reaction of fibrinogen to platelets. 67
Carbamazepine interaction with direct oral anticoagulants: help from the laboratory for the personalized management of oral anticoagulant therapy 67
Placental-derived PGI2 inhibits cord blood platelet function 66
Molecular Aggregation of Marketed Recombinant FVIII Products: Biochemical Evidence and Functional Effects. 66
Cystic fibrosis transmembrane conductance regulator (CFTR) expression in human platelets: impact on mediators and mechanisms of the inflammatory response 65
Hemophilia A and von Willebrand deficiency: therapeutic implications 65
Does chronic oral anticoagulation reduce in-hospital mortality among COVID-19 older patients? 65
Inherited macrothrombocytopenia with distinctive platelet ultrastructural and functional features 64
Another family with IGPS 64
β2 -Glycoprotein I binds to thrombin and selectively inhibits the enzyme procoagulant functions 64
Carbamazepine interaction with direct oral anticoagulants: help from the laboratory for the personalized management of oral anticoagulant therapy 64
ORal anticoagulants In fraGile patients with percutAneous endoscopic gastrostoMy and atrIal fibrillation: the (ORIGAMI) study 64
Proteolytic Processing of Von Willebrand Factor by Adamts13 and Leukocyte Proteases 63
Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma 63
Detection of Platelet-Activating Antibodies Associated with Vaccine-Induced Thrombotic Thrombocytopenia by Flow Cytometry: An Italian Experience 63
Thrombin-thrombomodulin interaction: energetics and potential role of water as an allosteric effector. 62
Placental derived PGI2 inhibits cord platelet function:possible role of PGI in THR transient hyporeactivity of newborn platelets 62
Diagnosis and management of cerebral venous sinus thrombosis in children: a single-center retrospective analysis 62
Noncanonical type 2B von Willebrand disease associated with mutations in the VWF D9D3 and D4 domains 61
Heparin versus prostacyclin in continuous hemodiafiltration for acute renal failure: effects on platelet function in the systemic circulation and across the filter 60
Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma 60
The expanding spectrum of PRPS1-associated phenotypes: three novel mutations segregating with X-linked hearing loss and mild peripheral neuropathy 60
From angiotensin-converting enzyme 2 disruption to thromboinflammatory microvascular disease: A paradigm drawn from COVID-19 59
Relevance of chloride binding to von Willebrand factor in type 2B von Willebrand disease patients 58
Plasma protein oxidation is associated with an increase of procoagulant markers causing an imbalance between pro- and anticoagulant pathways in healthy subjects 58
A recurrent Gly43Asp substitution in coagulation Factor X rigidifies its catalytic pocket and impairs catalytic activity and intracellular trafficking 58
Ristocetin-induced self-aggregation of von Willebrand factor. 57
High-mobility group box-1 protein promotes angiogenesis after peripheral ischemia in diabetic mice through a VEGF-dependent mechanism 57
Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients 56
Wiskott-Aldrich syndrome: report of an autosomal dominant variant 56
The dominant-negative von Willebrand factor gene deletion p.P1127_C1948delinsR: molecular mechanism and modulation. 55
INHIBITION OF FIBRINOGEN BINDING TO HUMAN-PLATELETS BY BLOCKAGE OF NA+/H+ EXCHANGE. 55
Congenital prothrombin deficiency 55
Mechanistic studies on ADAMTS13 catalysis. 55
Perceived challenges and attitudes to regimen and product selection from Italian haemophilia treaters: the 2013 AICE survey 54
Apixaban Interacts with Haemoglobin: Effects on Its Plasma Levels 54
The linkage between binding of the C-terminal domain of hirudin and amidase activity in human alpha-thrombin 53
Carbon monoxyde and oxygen binding to human hemoglobin F0. 53
Oral anticoagulants in fragile patients with percutaneous endoscopic gastrostomy and atrial fibrillation: the ORIGAMI pilot investigation 53
Thrombin interaction with platelet GpIB: role of the heparin binding domain. 52
Heparin versus prostacyclin in continuous hemodiafiltration for acute renal failure: effects on platelet function in the systemic circulation and across the filter 52
Allosteric modulation of BPTI interaction with human alpha- and zeta-thrombin. 50
Binding of human alpha-thrombin to platelet GpIb: energetics and functional effects. 49
Fibrinogen-elongated gamma chain inhibits thrombin-induced platelet response, hindering the interaction with different receptors 49
On-pump Cardiac Surgery Enhances Platelet Renewal and Impairs Aspirin Pharmacodynamics: Effects of Improved Dosing Regimens 49
Mechanochemistry of von Willebrand factor 49
Sustained safe and effective anticoagulation using Edoxaban via percutaneous endoscopic gastrostomy 49
Lipid and protein oxidation contribute to a prothrombotic state in patients with type 2 diabetes mellitus. 46
Measurement of plasma fibrinogen concentration by the prothrombin-time-derived method: applicability and limitations. 45
Mechanistic studies on ADAMTS13 catalysis 44
KINETIC ASPECTS OF RELEASE OF FIBRINOPEPTIDES AP AND AY BY HUMAN ALPHA-THROMBIN 43
Current Choices and Management of Treatment in Persons with Severe Hemophilia A without Inhibitors: A Mini‐Delphi Consensus 43
Fibrinogen-elongated gamma chain inhibits thrombin-induced platelet response, hindering the interaction with different receptors 42
Italian intersociety consensus on DOAC use in internal medicine 41
Sustained safe and effective anticoagulation using Edoxaban via percutaneous endoscopic gastrostomy 41
Increased von Willebrand factor levels in polycythemia vera and phenotypic differences with essential thrombocythemia 41
The use of viscoelastic haemostatic assays in non-cardiac surgical settings: A systematic review and meta-analysis 39
TEMPERATURE-DEPENDENCE AND PH-DEPENDENCE OF THE OXYGEN-BINDING REACTION OF HUMAN-FETAL HEMOGLOBIN. 39
The P303T mutation in the human factor VII (FVII) gene alters the conformational state of the enzyme and causes a severe functional deficiency. 39
Totale 7.519
Categoria #
all - tutte 37.764
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.764


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020930 0 0 92 85 78 124 127 34 79 71 133 107
2020/2021995 36 112 27 100 150 50 109 19 117 76 166 33
2021/20221.124 83 114 24 62 64 35 34 173 60 54 206 215
2022/20231.973 264 318 165 259 155 233 80 171 230 26 56 16
2023/20241.134 41 316 30 78 49 203 66 61 17 39 102 132
2024/202598 56 42 0 0 0 0 0 0 0 0 0 0
Totale 8.524