Pregnancy after bariatric surgery is usually considered safe. Recently, a few studies reported that bariatric surgery represents a risk factor for birth defects. A case series of six patients, born from women who had undergone biliopancreatic diversion, is reported. The clinical pattern was characterized by psychomotor development delay (100%), microphthalmia (83%), growth retardation (66%), hearing loss (66%), and variable facial dysmorphism. Based on the clinical profile and symptoms reported by women during pregnancy, a causal association between maternal chronic post-surgical malabsorption, congenital anomalies, and neonatal outcome is proposed, with vitamin A deficiency representing a major causing factor. Educational follow-up support, continuous clinical monitoring, and appropriate nutritional assessment appear to be crucial to reduce the potential risk of congenital malformations and child disability.

Onesimo, R., Proli, F., Leoni, C., Contaldo, I., Salerni, A., Conti, G., Tartaglia, M., Zampino, G., Embryopathy Following Maternal Biliopancreatic Diversion: Is Bariatric Surgery Really Safe?, <<OBESITY SURGERY>>, 2020; (Jul 28): N/A-N/A. [doi:10.1007/s11695-020-04882-w] [http://hdl.handle.net/10807/166664]

Embryopathy Following Maternal Biliopancreatic Diversion: Is Bariatric Surgery Really Safe?

Onesimo, R.;Leoni, C.;Contaldo, I.;Salerni, A.;Conti, G.;Zampino, G.
2020

Abstract

Pregnancy after bariatric surgery is usually considered safe. Recently, a few studies reported that bariatric surgery represents a risk factor for birth defects. A case series of six patients, born from women who had undergone biliopancreatic diversion, is reported. The clinical pattern was characterized by psychomotor development delay (100%), microphthalmia (83%), growth retardation (66%), hearing loss (66%), and variable facial dysmorphism. Based on the clinical profile and symptoms reported by women during pregnancy, a causal association between maternal chronic post-surgical malabsorption, congenital anomalies, and neonatal outcome is proposed, with vitamin A deficiency representing a major causing factor. Educational follow-up support, continuous clinical monitoring, and appropriate nutritional assessment appear to be crucial to reduce the potential risk of congenital malformations and child disability.
Inglese
Onesimo, R., Proli, F., Leoni, C., Contaldo, I., Salerni, A., Conti, G., Tartaglia, M., Zampino, G., Embryopathy Following Maternal Biliopancreatic Diversion: Is Bariatric Surgery Really Safe?, <<OBESITY SURGERY>>, 2020; (Jul 28): N/A-N/A. [doi:10.1007/s11695-020-04882-w] [http://hdl.handle.net/10807/166664]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/166664
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