We present the case of a young man admitted to our hospital for persistent headache associated with fever, retrorbitary pain and vomiting, who rapidly developed encephalopathy with drowsiness, paraplegia, hypoesthesia with a D6 sensory level and urinary retention. Brain and spinal cord MRI revealed findings compatible with acute disseminated encephalomyelitis (ADEM) and microbiological tests documented a cytomegalovirus (CMV) infection. CMV infection is extraordinarily associated with ADEM, but must be included in microbiological tests, because early diagnosis and treatment ameliorate the neurological outcome.
De Fino, C., Nociti, V., Modoni, A., Bizzarro, A., Mirabella, M., An atypical case of acute disseminated encephalomyelitis associated with cytomegalovirus infection, <<MULTIPLE SCLEROSIS AND RELATED DISORDERS>>, 2016; 5 (Jan): 70-2-72. [doi:10.1016/j.msard.2015.11.003] [http://hdl.handle.net/10807/77792]
An atypical case of acute disseminated encephalomyelitis associated with cytomegalovirus infection
De Fino, ChiaraPrimo
;Nociti, VivianaSecondo
;Modoni, Anna;Bizzarro, AlessandraPenultimo
;Mirabella, MassimilianoUltimo
2016
Abstract
We present the case of a young man admitted to our hospital for persistent headache associated with fever, retrorbitary pain and vomiting, who rapidly developed encephalopathy with drowsiness, paraplegia, hypoesthesia with a D6 sensory level and urinary retention. Brain and spinal cord MRI revealed findings compatible with acute disseminated encephalomyelitis (ADEM) and microbiological tests documented a cytomegalovirus (CMV) infection. CMV infection is extraordinarily associated with ADEM, but must be included in microbiological tests, because early diagnosis and treatment ameliorate the neurological outcome.
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