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EnglishEncapsulating peritoneal sclerosis is a serious complication of peritoneal dialysis and can occur even after transplant. The gut is partially or totally enveloped by a thick fibrous membrane that leads to the formation of multiple sections containing intestinal loops contracted and reduced in volume. Exacerbation after renal transplantation is a very rare but sometimes dramatic condition. We report a patient who developed intestinal obstruction due to encapsulating peritoneal sclerosis 1 year after a deceased-donor kidney transplant. Treatment included laparotomy, small-bowel lengthening by release of adhesions, and high doses of corticosteroids. The patient received immunosuppressive therapy with a combination of low-dose cyclosporine, everolimus, and prednisone, unchanged except for a temporary steroid increase in the postoperative period. We report success with this combined surgical plus medical therapy, with no recurrence after 81 months of follow-up.
Romagnoli, J., Pedroso, J. A. R., Salerno, M. P., Favi, E., Spagnoletti, G., Citterio, F., Posttransplant encapsulating peritoneal sclerosis, long-term success with everolimus and low-dose CNI: a case report, <<TRANSPLANTATION PROCEEDINGS>>, 2014; 46 (7): 2368-2370. [doi:10.1016/j.transproceed.2014.07.060] [http://hdl.handle.net/10807/71569]
| Autori: | |
| Titolo: | Posttransplant encapsulating peritoneal sclerosis, long-term success with everolimus and low-dose CNI: a case report |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.transproceed.2014.07.060 |
| Data di pubblicazione: | 2014 |
| Abstract: | Encapsulating peritoneal sclerosis is a serious complication of peritoneal dialysis and can occur even after transplant. The gut is partially or totally enveloped by a thick fibrous membrane that leads to the formation of multiple sections containing intestinal loops contracted and reduced in volume. Exacerbation after renal transplantation is a very rare but sometimes dramatic condition. We report a patient who developed intestinal obstruction due to encapsulating peritoneal sclerosis 1 year after a deceased-donor kidney transplant. Treatment included laparotomy, small-bowel lengthening by release of adhesions, and high doses of corticosteroids. The patient received immunosuppressive therapy with a combination of low-dose cyclosporine, everolimus, and prednisone, unchanged except for a temporary steroid increase in the postoperative period. We report success with this combined surgical plus medical therapy, with no recurrence after 81 months of follow-up. |
| Lingua: | Inglese |
| Rivista: | |
| Citazione: | Romagnoli, J., Pedroso, J. A. R., Salerno, M. P., Favi, E., Spagnoletti, G., Citterio, F., Posttransplant encapsulating peritoneal sclerosis, long-term success with everolimus and low-dose CNI: a case report, <<TRANSPLANTATION PROCEEDINGS>>, 2014; 46 (7): 2368-2370. [doi:10.1016/j.transproceed.2014.07.060] [http://hdl.handle.net/10807/71569] |
| Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |
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