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EnglishPseudohypoparathyroidism type 1A and its association with bipolar disorder (BD) have never been reported so far. We report a new case with both clinical entities and discuss the potential pathophysiological mechanisms of this association (protein kinase A hypoactivation, parathyroid hormone, hypocalcemia, protein kinase C activation, vitamin D deficiency). In this patient, the correction of the underlying calcium and vitamin D deficiencies leads to a better BD outcome and lower dosage of psychopharmacological agents. The conclusions might be generalized for a better understanding and management of these conditions
Kadilli, I., Colicchio, S., Guglielmo, R., Vollono, C., Della Marca, G., Janiri, L., Clinical insights by the presence of bipolar disorder in pseudohypoparathyroidism type 1A, <<GENERAL HOSPITAL PSYCHIATRY>>, 2015; (Settembre): 497-497. [doi:10.1016/j.genhosppsych.2015.06.008] [http://hdl.handle.net/10807/67692]
| Autori: | |
| Titolo: | Clinical insights by the presence of bipolar disorder in pseudohypoparathyroidism type 1A |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.genhosppsych.2015.06.008 |
| Data di pubblicazione: | 2015 |
| Abstract: | Pseudohypoparathyroidism type 1A and its association with bipolar disorder (BD) have never been reported so far. We report a new case with both clinical entities and discuss the potential pathophysiological mechanisms of this association (protein kinase A hypoactivation, parathyroid hormone, hypocalcemia, protein kinase C activation, vitamin D deficiency). In this patient, the correction of the underlying calcium and vitamin D deficiencies leads to a better BD outcome and lower dosage of psychopharmacological agents. The conclusions might be generalized for a better understanding and management of these conditions |
| Lingua: | Inglese |
| Rivista: | |
| Citazione: | Kadilli, I., Colicchio, S., Guglielmo, R., Vollono, C., Della Marca, G., Janiri, L., Clinical insights by the presence of bipolar disorder in pseudohypoparathyroidism type 1A, <<GENERAL HOSPITAL PSYCHIATRY>>, 2015; (Settembre): 497-497. [doi:10.1016/j.genhosppsych.2015.06.008] [http://hdl.handle.net/10807/67692] |
| Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |
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