Coronavirus disease-19 (COVID-19) is a predominantly respiratory syndrome. Growing reports about a SARS-CoV-2 neurological involvement, including autonomic dysfunction (AD), have been reported, mostly in critically-ill patients, or in the long-COVID syndrome. In this observational, cross-sectional study, we investigated the prevalence of AD in 20 non-critically-ill COVID-19 patients (COVID+ group) in the acute phase of the disease through a composite instrumental evaluation consisting of Sudoscan, automated pupillometry, heart rate variability (HRV), and pulse transit time (PTT). All the parameters were compared to a control group of 20 healthy volunteers (COVID- group). COVID+ group presented higher values of pupillary dilatation velocities, and baseline pupil diameter than COVID- subjects. Moreover, COVID+ patients presented a higher incidence of feet sudomotor dysfunction than COVID- group. No significant differences emerged in HRV and PTT parameters between groups. In this study we observed the occurrence of autonomic dysfunction in the early stage of the disease.

Bellavia, S., Scala, I., Luigetti, M., Brunetti, V., Gabrielli, M., Zileri Dal Verme, L., Servidei, S., Calabresi, P., Frisullo, G., Della Marca, G., Instrumental Evaluation of COVID-19 Related Dysautonomia in Non-Critically-Ill Patients: An Observational, Cross-Sectional Study, <<JOURNAL OF CLINICAL MEDICINE>>, 2021; 10 (24): 5861-N/A. [doi:10.3390/jcm10245861] [https://hdl.handle.net/10807/232539]

Instrumental Evaluation of COVID-19 Related Dysautonomia in Non-Critically-Ill Patients: An Observational, Cross-Sectional Study

Bellavia, Simone;Scala, Irene;Luigetti, Marco;Brunetti, Valerio;Gabrielli, Maurizio;Zileri Dal Verme, Lorenzo;Servidei, Serenella;Calabresi, Paolo;Frisullo, Giovanni;Della Marca, Giacomo
2021

Abstract

Coronavirus disease-19 (COVID-19) is a predominantly respiratory syndrome. Growing reports about a SARS-CoV-2 neurological involvement, including autonomic dysfunction (AD), have been reported, mostly in critically-ill patients, or in the long-COVID syndrome. In this observational, cross-sectional study, we investigated the prevalence of AD in 20 non-critically-ill COVID-19 patients (COVID+ group) in the acute phase of the disease through a composite instrumental evaluation consisting of Sudoscan, automated pupillometry, heart rate variability (HRV), and pulse transit time (PTT). All the parameters were compared to a control group of 20 healthy volunteers (COVID- group). COVID+ group presented higher values of pupillary dilatation velocities, and baseline pupil diameter than COVID- subjects. Moreover, COVID+ patients presented a higher incidence of feet sudomotor dysfunction than COVID- group. No significant differences emerged in HRV and PTT parameters between groups. In this study we observed the occurrence of autonomic dysfunction in the early stage of the disease.
2021
Inglese
Bellavia, S., Scala, I., Luigetti, M., Brunetti, V., Gabrielli, M., Zileri Dal Verme, L., Servidei, S., Calabresi, P., Frisullo, G., Della Marca, G., Instrumental Evaluation of COVID-19 Related Dysautonomia in Non-Critically-Ill Patients: An Observational, Cross-Sectional Study, <<JOURNAL OF CLINICAL MEDICINE>>, 2021; 10 (24): 5861-N/A. [doi:10.3390/jcm10245861] [https://hdl.handle.net/10807/232539]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/232539
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