: The clinical, radiological, neurophysiological and neuropsychological findings of three patients with giant subcortical heterotopia are reported. All patients experienced psychomotor and behaviour improvement after surgery. Two subjects are seizure-free after complete excision of the heterotopia; the third patient significantly improved following subtotal removal (Engel's class II). Patients affected by giant subcortical heterotopias can have a favourable prognosis after the surgical removal of the malformation, even following long-lasting epilepsy.
Novegno, F., Battaglia, D. I., Chieffo, D. P. R., Frassanito, P., Leoni, C., Tamburrini, G., Massimi, L., Tartaglione, T., Di Rocco, C., Guzzetta, F., Giant subcortical heterotopia involving the temporo-parieto-occipital region: a challenging cause of drug-resistant epilepsy, <<EPILEPSY RESEARCH>>, 2009; 87 (1): 88-94. [doi:10.1016/j.eplepsyres.2009.06.006] [https://hdl.handle.net/10807/223529]
Giant subcortical heterotopia involving the temporo-parieto-occipital region: a challenging cause of drug-resistant epilepsy
Battaglia, Domenica Immacolata;Chieffo, Daniela Pia Rosaria;Frassanito, Paolo;Leoni, Chiara;Tamburrini, Gianpiero;Massimi, Luca;Tartaglione, Tommaso;
2009
Abstract
: The clinical, radiological, neurophysiological and neuropsychological findings of three patients with giant subcortical heterotopia are reported. All patients experienced psychomotor and behaviour improvement after surgery. Two subjects are seizure-free after complete excision of the heterotopia; the third patient significantly improved following subtotal removal (Engel's class II). Patients affected by giant subcortical heterotopias can have a favourable prognosis after the surgical removal of the malformation, even following long-lasting epilepsy.
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