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Prognostic factors in hodgkin lymphoma

: Hodgkin lymphoma (HL) is among the neoplastic diseases that has the best long-term outcome after cytotoxic treatment. Cure rates approach 80-90%; however, 15-20% of patients will be resistant to therapy (primary refractory) or relapse after treatment. Prognostic factors should help to stratify treatment according to the risk profile and identify patients at risk for failure. Significance of prognostic factors partly depends on the efficacy of the treatments administered, since new effective...

The leakage effect may undermine the circular economy efforts

In this paper, we examine the impact of the circular economy on global resource extraction. To this end, we make an input–output analysis dynamic by combining it with an agent-based model of the capital sector. This approach allows us to study the evolution of the circular economy due to the endogenous decisions of firms on whether to invest in the capital expansion of primary or secondary sectors. Previous studies have examined the macroeconomic effects of the circular economy using scenario...

Multiplicity and not necessarily heterogeneity: implications for the long-run degree of capacity utilization

The paper discusses the implications of disaggregation within the post-Keynesian debate on the long-run convergence of the degree of capacity utilization toward the normal one. The debate is related to the emergence of Harrodian instability inside multiplier–accelerator models and has been characterized by two “opposite” positions: the supermultiplier (SM) and the neo-Kaleckian approaches. These approaches solve the instability issue diferently, but both share the postulate that an equil...

The circular economy mitigates the material rebound due to investments in renewable energy

The current macroeconomic models of the circular economy rely on the unrealistic assumption that materials can be recycled infinitely, often ignoring price and demand adjustments. In reality, most virgin materials are recycled only a few times, while the proliferation of cheap products made from recycled materials is likely to affect final demand. In this paper, we address both of these shortcomings. We propose a novel climate-economy agent-based model of the circular economy combined with th...

Revolutionizing Healthcare: Unveiling the Transformative Power of Chatbots Through a Systematic Literature Review

In the digital age, the healthcare industry is evolving and playing a key role in optimizing the patient care and wellness process. In this scenario, most prominent disruptive technology appears in chatbots, i.e., digital tools that are revolutionizing the healthcare landscape (Mariani et al., 2023). By definition, chatbots are virtual assistants that, through a sophisticated algorithm, can respond to and communicate with people who interface with them through both text and voice. In most cas...

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