Il sistema di repository digitale IRIS acquisisce, archivia, indicizza, conserva e rende accessibili prodotti digitali della ricerca. https://publicatt.unicatt.it:443 2026-05-15T13:18:10Z 2026-05-15T13:18:10Z https://hdl.handle.net/10807/335840.2 2026-05-15T13:17:39Z 2026-01-01T00:00:00Z

Titolo: Sulle tracce di un esploratore eccentrico. Intervista con Morten Strøksnes sul romanzo «Il fantasma di Lumholtz» (Iperborea) Autori: Ingrid Basso Abstract: In un’epoca in cui le scienze sociali empiriche ancora non avevano un proprio statuto autonomo e i viaggi di esplorazione nella maggior parte dei casi altro non erano che un sottoprodotto del colonialismo, un poco convinto teologo norvegese molto più appassionato di tassidermia che di catechesi, cura l’“esaurimento nervoso” che l’ha prostrato intorno ai trent’anni partendo per il primo di quelli che diventeranno leggendari viaggi di esplorazione. Nel 1880 alla volta delle foreste inesplorate del Queensland, a seguire Stati Uniti e Messico, infine il Borneo. Se all’inizio i suoi resoconti sembrano scritti per intrattenere un pubblico borghese sulle bizzarrie di cannibali, cacciatori di teste e animali quasi preistorici tra tribù “primitive”, nel corso dei decenni Lumholtz – già pionierie dell’osservazione partecipante in anticipo su Malinowski e, pur senza una specifica preparazione scientifica, collaboratore di Franz Boas – contribuisce alla vera e propria nascita dell’antropologia culturale.

2026-01-01T00:00:00Z https://hdl.handle.net/10807/335839 2026-05-15T13:15:06Z 2024-01-01T00:00:00Z

Titolo: Acute changes in serum inflammatory signatures after consumption of ready-to-drink immuno-nutrition: A case report Autori: Briguglio M.; Ragni E.; Langella F.; Scaramuzzo L.; Crespi T.; Wainwright T. W.; Banfi G.; Berjano P. Abstract: Background: Immuno-nutrition administers specific nutrients to improve host defences, in particular supporting the immune system. Given the high invasiveness of some spine operations, strengthening the immune response could effectively balance the surgical stress and boost resilience. However, it is not clear what are the early molecular signatures after the consumption of immuno-modulatory nutrients. Materials and methods: In the context of nutritional prehabilitation, we present the case of a lady with scoliosis scheduled for surgery who was administered immuno-nutrition preoperatively and tested for acute changes in 200 biomolecules after two and four hours. Results: After four hours, we mainly observed 30-fold increase in IL-10, 10-fold increase in IL-18 inhibitory protein, 6-fold increase in IL-1 inhibitory receptor, 12-fold decrease in IL-2 receptor, and 51-fold decrease in IL-23. Gene ontology annotations showed the involvement of genes regulating cytokine activity, response to external organisms, humoral and adaptive response, and lymphocyte immunity. Conclusion: Overall, the trends over the first four hours showed a positive shift of the cytokine balance in favour of anti-inflammatory mediators while keeping active the cell-mediated immunity. The use of immuno-nutrition for prehabilitation patients could prove useful to patients but benefits from chronic consumption and surgical outcomes remain to be determined.

2024-01-01T00:00:00Z https://hdl.handle.net/10807/335838 2026-05-15T13:10:01Z 2025-01-01T00:00:00Z

Titolo: Sacral and Pelvic Insufficiency Fractures Following Adult Spinal Deformity Surgery: A Case Report and Systematic Literature Review Autori: Velluto C.; Marciano A.; Vavalle G.; Borruto M. I.; Perna A.; Scaramuzzo L.; Proietti L. Abstract: Background: Sacral and pelvic insufficiency fractures (SIFs and PIFs) are increasingly recognized yet frequently underdiagnosed complications after adult spinal deformity (ASD) surgery, particularly in patients undergoing long-segment spinal fusion to the sacrum or pelvis. Methods: We present a representative case of sacral and pelvic insufficiency fractures following extensive spinal fusion, highlighting diagnostic and therapeutic challenges. In addition, a systematic review of the literature was performed according to PRISMA guidelines through PubMed, MEDLINE, and Scopus databases, including studies up to December 2024. Data regarding demographics, risk factors, diagnostic modalities, management strategies, and outcomes were extracted and narratively synthesized. Results: A total of 21 studies comprising 89 patients were included. The majority were elderly postmenopausal women with osteoporosis and additional risk factors such as chronic corticosteroid therapy or high body mass index. Diagnosis was frequently delayed due to low sensitivity of plain radiographs, whereas computed tomography was the most reliable modality. Management was surgical in 49 patients (55%)—most commonly extension of fixation to the pelvis or use of S2-alar-iliac screws—with favorable fracture healing reported in most cases. Conservative treatment, employed in 40 patients (45%), included bracing, restricted activity, and bone health optimization, also leading to healing in the majority of cases. Conclusions: Sacral and pelvic insufficiency fractures represent an underrecognized but clinically significant complication after ASD surgery. Early recognition through cross-sectional imaging (CT/MRI) is crucial, and both surgical and conservative approaches can be effective if tailored to patient and fracture characteristics.

2025-01-01T00:00:00Z https://hdl.handle.net/10807/335837 2026-05-15T12:57:07Z 2024-01-01T00:00:00Z

Titolo: Radiological evaluation of fusion patterns after Lateral Lumbar Interbody fusion with 3D-printed porous titanium cages vs. conventional titanium cages Autori: Velluto C.; Mundis G.; Scaramuzzo L.; Perna A.; Capece G.; Cruciani A.; Inverso M.; Borruto M. I.; Proietti L. Abstract: Introduction: The assessment of segmental fusion after Lateral Lumbar Interbody fusion (LLIF) using 3D-printed porous titanium cage is still not well studied. Various criteria, such as the presence of bone bridges (BB) between adjacent vertebrae, serve as indicators for anterior fusion. However, limited radiological studies have investigated zygapophyseal joints (ZJ) status following LLIF with porous titanium cages vs. conventional titanium threaded cages. The porous design of the latest titanium intervertebral cages is thought to enhance the bone-to-implant fusion rate. This radiological study aimed to compare the fusion patterns post-LLIF using 3D-printed porous titanium cages against those using threaded titanium cages. This radiological study aimed to compare the fusion patterns after LLIF using 3D-printed porous titanium cages against those using threaded titanium cages. Material and methods: This retrospective, single-center radiological study involved 135 patients who underwent LLIF and posterior percutaneous screw fixation for degenerative spondylolisthesis. The study included 51 patients (Group A) with the novel porous titanium cages and 84 patients (Group B) with conventional threaded titanium cages. Inclusion criteria mandated complete radiological data and a minimum follow-up period of 24 months. The study evaluated intervertebral bone bridges (BB) for anterior fusion and zygapophyseal joints (ZJ) ankylotic degeneration, based on Pathria et al., as evidence of posterior fusion and segmental immobilization. Results: Two years after surgery, intervertebral BB were identified in 83 segments (94.31%) in Group A and in 87 segments (88.77%) in Group B. ZJ Pathria grade I was observed in 2 segments (2.27%) of Group A and in 4 segments (4.08%) of Group B. Grade II was seen in 5 segments (5.68%) of Group A and in 6 segments (6.12%) of Group B. Posterior fusion, classified as grade III, was found in 81 segments (92.04%) of Group A and 88 segments (89.79%) of Group B. Subsidence incidence was 5.88% (3 segments) for the novel cage and 9.88% (8 segments) for the conventional cage. Conclusions: The architecture of porous titanium cages offers a promising solution for increasing bone ingrowth and bridging space, supporting successful spinal fusion while minimizing the risk of subsidence.

2024-01-01T00:00:00Z