Although the pathophysiology of gambling is unknown, an involvement of midbrain dopaminergic pathway has been hypothesized. In this study, the association between brain-derived neurotrophic factor (BDNF) and pathological gamblingwas investigated.We measured BDNF serum levels in (1) video players (n = 10); (2) card players (n = 9); (3) mixed players (n = 21; both video and card players) and (4) age-matched controls (n = 18). Mixed players had increased BDNF serum levels as compared to controls and higher South Oaks Gambling Screen score as compared to card or video players. Thus, the data demonstrate that patients affected by severe pathological gambling showenhanced BDNF serum levels.

Angelucci, F., Martinotti, G., Gelfo, F., Righino, E., Conte, G., Caltagirone, C., Bria, P., Enhanced BDNF serum levels in patients with severe pathological gambling, <<ADDICTION BIOLOGY>>, 2011; 18 (N/A): 749-751. [doi:10.1111/j.1369-1600.2011.00411.x] [http://hdl.handle.net/10807/9893]

Enhanced BDNF serum levels in patients with severe pathological gambling

Martinotti, Giovanni;Righino, Elisabetta;Conte, Gianluigi;Bria, Pietro
2011

Abstract

Although the pathophysiology of gambling is unknown, an involvement of midbrain dopaminergic pathway has been hypothesized. In this study, the association between brain-derived neurotrophic factor (BDNF) and pathological gamblingwas investigated.We measured BDNF serum levels in (1) video players (n = 10); (2) card players (n = 9); (3) mixed players (n = 21; both video and card players) and (4) age-matched controls (n = 18). Mixed players had increased BDNF serum levels as compared to controls and higher South Oaks Gambling Screen score as compared to card or video players. Thus, the data demonstrate that patients affected by severe pathological gambling showenhanced BDNF serum levels.
2011
Inglese
Angelucci, F., Martinotti, G., Gelfo, F., Righino, E., Conte, G., Caltagirone, C., Bria, P., Enhanced BDNF serum levels in patients with severe pathological gambling, <<ADDICTION BIOLOGY>>, 2011; 18 (N/A): 749-751. [doi:10.1111/j.1369-1600.2011.00411.x] [http://hdl.handle.net/10807/9893]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/9893
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