OBJECTIVES: This study was conceived to compare the results of aortic root replacement using a composite biological valved graft with or without neo-sinuses of Valsalva. METHODS: We compared the early clinical outcomes of 421 patients who underwent aortic root replacement using a handmade biological composite valved graft with or without neo-sinuses (198 and 223 patients, respectively). Propensity matching based on the most important preoperative clinical variables resulted in a cohort of 210 patients (105 pairs) with comparable baseline variables. RESULTS: No difference in early clinical outcome was found between the unmatched groups. At a mean follow-up of 28.8 months, 11 patients required reoperation on the aortic valve (2.6%). Seven of the cases of reoperation were in the group without neo-sinuses (P = 0.83). In the propensity-matched groups, the type of graft used did not affect early and late clinical outcome and incidence of reoperations. CONCLUSIONS: The early clinical outcome of patients submitted to aortic root replacement using a handmade biological composite valved graft is equally good in the presence and in the absence of neo-sinuses

Gaudino, M. F. L., Weltert, L., Munjal, M., Lau, C., Elsayed, M., Salica, A., Gambardella, I., Mills, E., De Paulis, R., Girardi, L. N., Early clinical outcome after aortic root replacement using a biological composite valved graft with and without neo-sinuses, <<EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY>>, 2016; (N/A): N/A-N/A. [doi:10.1093/ejcts/ezw253] [http://hdl.handle.net/10807/93702]

Early clinical outcome after aortic root replacement using a biological composite valved graft with and without neo-sinuses

Gaudino
Primo
;
Mohamed; Salica;
2016

Abstract

OBJECTIVES: This study was conceived to compare the results of aortic root replacement using a composite biological valved graft with or without neo-sinuses of Valsalva. METHODS: We compared the early clinical outcomes of 421 patients who underwent aortic root replacement using a handmade biological composite valved graft with or without neo-sinuses (198 and 223 patients, respectively). Propensity matching based on the most important preoperative clinical variables resulted in a cohort of 210 patients (105 pairs) with comparable baseline variables. RESULTS: No difference in early clinical outcome was found between the unmatched groups. At a mean follow-up of 28.8 months, 11 patients required reoperation on the aortic valve (2.6%). Seven of the cases of reoperation were in the group without neo-sinuses (P = 0.83). In the propensity-matched groups, the type of graft used did not affect early and late clinical outcome and incidence of reoperations. CONCLUSIONS: The early clinical outcome of patients submitted to aortic root replacement using a handmade biological composite valved graft is equally good in the presence and in the absence of neo-sinuses
Inglese
Gaudino, M. F. L., Weltert, L., Munjal, M., Lau, C., Elsayed, M., Salica, A., Gambardella, I., Mills, E., De Paulis, R., Girardi, L. N., Early clinical outcome after aortic root replacement using a biological composite valved graft with and without neo-sinuses, <<EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY>>, 2016; (N/A): N/A-N/A. [doi:10.1093/ejcts/ezw253] [http://hdl.handle.net/10807/93702]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/93702
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