emophagocytic lymphohistiocytosis is a potentially fatal disorder resulting from excessive activation and non-malignant proliferation of T lymphocytes and macrophages. Neoplasms, autoimmune disorders and systemic infections can cause secondary hemophagocytic syndrome. The association of hemophagocytic syndrome and visceral leishmaniasis is rarely found in childhood. We report a case of an infant affected by hemophagocytic lymphohistiocytosis secondary to visceral leishamniasis and describe all cases of hemophagocytic syndrome associated with visceral leishamniasis in childhood reported in literature, focusing on clinical manifestation, diagnosis and treatment.

Scalzone, M., Ruggiero, A., Mastrangelo, S., Trombatore, G., Ridola, V., Maurizi, P., Riccardi, R., Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: case report and systematic review of literature, <<JOURNAL OF INFECTION IN DEVELOPING COUNTRIES>>, 2016; 10 (1): 103-108. [doi:10.3855/jidc.6385] [http://hdl.handle.net/10807/91856]

Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: case report and systematic review of literature

Scalzone, Maria
Primo
;
Ruggiero, Antonio
Secondo
;
Mastrangelo, Stefano;Trombatore, Giovanna;Ridola, Vita;Maurizi, Palma
Penultimo
;
Riccardi, Riccardo
Ultimo
2016

Abstract

emophagocytic lymphohistiocytosis is a potentially fatal disorder resulting from excessive activation and non-malignant proliferation of T lymphocytes and macrophages. Neoplasms, autoimmune disorders and systemic infections can cause secondary hemophagocytic syndrome. The association of hemophagocytic syndrome and visceral leishmaniasis is rarely found in childhood. We report a case of an infant affected by hemophagocytic lymphohistiocytosis secondary to visceral leishamniasis and describe all cases of hemophagocytic syndrome associated with visceral leishamniasis in childhood reported in literature, focusing on clinical manifestation, diagnosis and treatment.
Inglese
Scalzone, M., Ruggiero, A., Mastrangelo, S., Trombatore, G., Ridola, V., Maurizi, P., Riccardi, R., Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: case report and systematic review of literature, <<JOURNAL OF INFECTION IN DEVELOPING COUNTRIES>>, 2016; 10 (1): 103-108. [doi:10.3855/jidc.6385] [http://hdl.handle.net/10807/91856]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/91856
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