Micro-Abstract Asymmetric increase in breast vascularity (AIBV) is an emerging marker in magnetic resonance imaging-based evaluation of breast cancer. We analyze herein the largest series so far aimed at elucidating the potential role of AIBV in predicting the early and late outcomes of locally advanced breast cancer. We observed that, despite more aggressive pathologic profile of tumors associated with AIBV, they also present greater sensitivity to neoadjuvant chemotherapy. Nonetheless, the persistence of AIBV after neoadjuvant chemotherapy is associated with worse late prognosis and might be used to tailor additional treatments.
Bufi, E., Belli, P., Di Matteo, M., Giuliani, M., Tumino, M., Rinaldi, P., Nardone, L., Franceschini, G., Mule', A., Bonomo, L., Hypervascularity Predicts Complete Pathologic Response to Chemotherapy and Late Outcomes in Breast Cancer, <<CLINICAL BREAST CANCER>>, 2016; 16 (6): e193-e201. [doi:10.1016/j.clbc.2016.06.007] [http://hdl.handle.net/10807/91621]
Hypervascularity Predicts Complete Pathologic Response to Chemotherapy and Late Outcomes in Breast Cancer
Bufi, Enida
;Belli, PaoloSecondo
;Di Matteo, Marialuisa;Giuliani, Michela;Tumino, Mariavalentina;Rinaldi, Pierluigi;Nardone, Luigia;Franceschini, Gianluca;Mule', AntoninoPenultimo
;Bonomo, LorenzoUltimo
2016
Abstract
Micro-Abstract Asymmetric increase in breast vascularity (AIBV) is an emerging marker in magnetic resonance imaging-based evaluation of breast cancer. We analyze herein the largest series so far aimed at elucidating the potential role of AIBV in predicting the early and late outcomes of locally advanced breast cancer. We observed that, despite more aggressive pathologic profile of tumors associated with AIBV, they also present greater sensitivity to neoadjuvant chemotherapy. Nonetheless, the persistence of AIBV after neoadjuvant chemotherapy is associated with worse late prognosis and might be used to tailor additional treatments.
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