An up-to-date review on neuropsychological phenotypes in Dravet syndrome is reported. After recalling the results of various though not numerous studies in the literature, primarily retrospectively, the hypothesis of an original neuropsychological phenotype in Dravet syndrome is presented, consisting of a defect in sensorimotor integration, especially of visuoconstructive abilities. That is particularly evident in the less impaired patients and in the first several years of life. This core phenotype is eventually considered inside the analysis of the etiological multifactorial origin of the cognitive decline, which is especially expressed by the encephalopathy/channelopathy controversy.
Battaglia, D. I., Ricci, D., Chieffo, D. P. R., Guzzetta, F., Outlining a core neuropsychological phenotype for Dravet syndrome, <<EPILEPSY RESEARCH>>, 2016; 120 (Feb): 91-7-97. [doi:10.1016/j.eplepsyres.2015.11.020] [https://hdl.handle.net/10807/79591]
Outlining a core neuropsychological phenotype for Dravet syndrome
Battaglia, Domenica ImmacolataPrimo
;Ricci, DanielaSecondo
;Chieffo, Daniela Pia RosariaPenultimo
;Guzzetta, FrancescoUltimo
2016
Abstract
An up-to-date review on neuropsychological phenotypes in Dravet syndrome is reported. After recalling the results of various though not numerous studies in the literature, primarily retrospectively, the hypothesis of an original neuropsychological phenotype in Dravet syndrome is presented, consisting of a defect in sensorimotor integration, especially of visuoconstructive abilities. That is particularly evident in the less impaired patients and in the first several years of life. This core phenotype is eventually considered inside the analysis of the etiological multifactorial origin of the cognitive decline, which is especially expressed by the encephalopathy/channelopathy controversy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.