The need of adenosine administration for the achievement of maximal hyperaemia limits the widespread application of fractional flow reserve (FFR) in the real world. We hypothesised that Pd/Pa ratio registered during submaximal reactive hyperaemia induced by conventional non-ionic radiographic contrast medium (contrast medium induced Pd/Pa ratio: CMR) can be sufficient for the assessment of physiological severity of stenosis in the vast majority of cases. The aim of the present study was to test the accuracy of CMR in comparison to FFR.
Leone, A. M., Scalone, G., De Maria, G. L., Tagliaferro, F., Gardi, A., Di Clemente, F., Basile, E., Cialdella, P., De Caterina, A., Porto, I., Aurigemma, C., Burzotta, F., Niccoli, G., Trani, C., Rebuzzi, A. G., Crea, F., Efficacy of contrast medium induced Pd/Pa ratio in predicting functional significance of intermediate coronary artery stenosis assessed by fractional flow reserve: insights from the RINASCI study, <<EUROINTERVENTION>>, 2015; 11 (4): 421-427. [doi:10.4244/EIJY14M07_02] [http://hdl.handle.net/10807/69380]
Efficacy of contrast medium induced Pd/Pa ratio in predicting functional significance of intermediate coronary artery stenosis assessed by fractional flow reserve: insights from the RINASCI study
Leone, Antonio Maria;Scalone, Giancarla;De Maria, Giovanni Luigi;Di Clemente, Francesca;Basile, Eloisa;Cialdella, Pio;De Caterina, Alberto;Porto, Italo;Aurigemma, Cristina;Burzotta, Francesco;Niccoli, Giampaolo;Trani, Carlo;Rebuzzi, Antonio Giuseppe;Crea, Filippo
2015
Abstract
The need of adenosine administration for the achievement of maximal hyperaemia limits the widespread application of fractional flow reserve (FFR) in the real world. We hypothesised that Pd/Pa ratio registered during submaximal reactive hyperaemia induced by conventional non-ionic radiographic contrast medium (contrast medium induced Pd/Pa ratio: CMR) can be sufficient for the assessment of physiological severity of stenosis in the vast majority of cases. The aim of the present study was to test the accuracy of CMR in comparison to FFR.
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