The high incidence of multidrug-resistant (MDR) bacteria among patients admitted to ICUs has determined an increase of tigecycline (TGC) use for the treatment of severe infections. Many concerns have been raised about the efficacy of this molecule and increased dosages have been proposed. Our purpose is to investigate TGC safety and efficacy at higher than standard doses.

De Pascale, G., Montini, L., Pennisi, M. A., Bernini, V., Maviglia, R., Bello, G., Spanu, T., Tumbarello, M., Antonelli, M., High dose tigecycline in critically ill patients with severe infections due to multidrug-resistant bacteria, <<CRITICAL CARE>>, 2014; 18 (3): R90-R90. [doi:10.1186/cc13858] [http://hdl.handle.net/10807/65015]

High dose tigecycline in critically ill patients with severe infections due to multidrug-resistant bacteria

De Pascale, Gennaro;Montini, Luca;Pennisi, Mariano Alberto;Bernini, Valentina;Maviglia, Riccardo;Bello, Giuseppe;Spanu, Teresa;Tumbarello, Mario;Antonelli, Massimo
2014

Abstract

The high incidence of multidrug-resistant (MDR) bacteria among patients admitted to ICUs has determined an increase of tigecycline (TGC) use for the treatment of severe infections. Many concerns have been raised about the efficacy of this molecule and increased dosages have been proposed. Our purpose is to investigate TGC safety and efficacy at higher than standard doses.
2014
Inglese
De Pascale, G., Montini, L., Pennisi, M. A., Bernini, V., Maviglia, R., Bello, G., Spanu, T., Tumbarello, M., Antonelli, M., High dose tigecycline in critically ill patients with severe infections due to multidrug-resistant bacteria, <<CRITICAL CARE>>, 2014; 18 (3): R90-R90. [doi:10.1186/cc13858] [http://hdl.handle.net/10807/65015]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/65015
Citazioni
  • ???jsp.display-item.citation.pmc??? 76
  • Scopus 198
  • ???jsp.display-item.citation.isi??? 163
social impact