Here we report a patient with a lymphoepithelial thymoma who developed in chronological sequence limbic encephalitis, neuromyotonia and myasthenia gravis. The patient presented with limbic encephalitis associated with an invasive thymoma and improved after surgery and cytotoxic therapy. Two months after thymectomy, neuromyotonia associated with hyperhidrosis and mild motor neuropathy occurred and the patient was given plasma-exchange and prednisone therapy. Five months later he developed mild generalised myasthenia gravis. Anti-acetylcholine receptor antibodies, previously repeatedly negative, were found positive at the onset of clinical signs of myasthenia gravis.

Evoli, A., Marra, R., Batocchi, A. P., Tonali, P. A., Lo Monaco, M., Lino, M., Multiple paraneoplastic diseases associated with thymoma., <<NEUROMUSCULAR DISORDERS>>, 1999; (9(8)): 601-603. [http://hdl.handle.net/10807/62914]

Multiple paraneoplastic diseases associated with thymoma.

Evoli, Amelia;Marra, Roberto;Batocchi, Anna Paola;Tonali, Pietro Attilio;Lo Monaco, Mauro;
1999

Abstract

Here we report a patient with a lymphoepithelial thymoma who developed in chronological sequence limbic encephalitis, neuromyotonia and myasthenia gravis. The patient presented with limbic encephalitis associated with an invasive thymoma and improved after surgery and cytotoxic therapy. Two months after thymectomy, neuromyotonia associated with hyperhidrosis and mild motor neuropathy occurred and the patient was given plasma-exchange and prednisone therapy. Five months later he developed mild generalised myasthenia gravis. Anti-acetylcholine receptor antibodies, previously repeatedly negative, were found positive at the onset of clinical signs of myasthenia gravis.
Inglese
Evoli, A., Marra, R., Batocchi, A. P., Tonali, P. A., Lo Monaco, M., Lino, M., Multiple paraneoplastic diseases associated with thymoma., <<NEUROMUSCULAR DISORDERS>>, 1999; (9(8)): 601-603. [http://hdl.handle.net/10807/62914]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/62914
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact