Raltegravir intensification is associated with an increase in 2-LTR episomal HIV DNA= circles, indicating a persistent low-level replication, in some individuals in ART with suppressed HIV RNA. We aimed at monitoring residual plasma HIV RNA and cellular HIV DNA in virologically suppressed patients switching to a raltegravir-based regimen.
Bianco, C., Meini, G., Rossetti, B., Lamonica, S., Mondi, A., Belmonti, S., Fanti, L., Ciccarelli, N., Di Giambenedetto, S., Zazzi, M., De Luca, A., Switch to raltegravir-based regimens and HIV DNA decrease in patients with suppressed HIV RNA, Abstract de <<HIV Drug Therapy Glasgow Congress 2014>>, (Glasgow, 23-26 October 2014 ), <<JOURNAL OF THE INTERNATIONAL AIDS SOCIETY>>, 2014; 17 (4 Suppl 3): 19791-19791. 10.7448/IAS.17.4.19791 [http://hdl.handle.net/10807/61290]
Switch to raltegravir-based regimens and HIV DNA decrease in patients with suppressed HIV RNA
Bianco, Claudia;Rossetti, Barbara;Mondi, Annalisa;Ciccarelli, Nicoletta;Di Giambenedetto, Simona;De Luca, Andrea
2014
Abstract
Raltegravir intensification is associated with an increase in 2-LTR episomal HIV DNA= circles, indicating a persistent low-level replication, in some individuals in ART with suppressed HIV RNA. We aimed at monitoring residual plasma HIV RNA and cellular HIV DNA in virologically suppressed patients switching to a raltegravir-based regimen.
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