Gemcitabine (2'-2'-difluorodeoxycytidine) is a well-known cytotoxic drug and a potent radio-enhancer. We herein report the in vitro evidence of its activity, and the clinical experiences when this drug is administered concurrently with radiation. The phase I-II trials are analyzed, focusing on the recent ability to deliver irradiation with low incidence of side effects.
Trodella, L., D'angelillo, R. M., Ramella, S., Cellini, N., Ciresa, M., Cesario, A., Granone, P., Chemo-radiotherapy in non-small cell lung cancer: the role of gemcitabine., <<ANNALS OF ONCOLOGY>>, 2006; (Maggio): 52-54 [http://hdl.handle.net/10807/5497]
Autori: | |
Titolo: | Chemo-radiotherapy in non-small cell lung cancer: the role of gemcitabine. |
Data di pubblicazione: | 2006 |
Abstract: | Gemcitabine (2'-2'-difluorodeoxycytidine) is a well-known cytotoxic drug and a potent radio-enhancer. We herein report the in vitro evidence of its activity, and the clinical experiences when this drug is administered concurrently with radiation. The phase I-II trials are analyzed, focusing on the recent ability to deliver irradiation with low incidence of side effects. |
Lingua: | Inglese |
Rivista: | |
Citazione: | Trodella, L., D'angelillo, R. M., Ramella, S., Cellini, N., Ciresa, M., Cesario, A., Granone, P., Chemo-radiotherapy in non-small cell lung cancer: the role of gemcitabine., <<ANNALS OF ONCOLOGY>>, 2006; (Maggio): 52-54 [http://hdl.handle.net/10807/5497] |
Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |