Fractional flow reserve (FFR) specifically relates to the severity of a stenosis to the mass of tissue to be perfused. Accordingly, the larger the territory to be perfused, the greater the flow and the pressure gradient induced by maximal hyperemia. Although this notion may be considered intuitive, its unequivocal demonstration is still lacking. The aim of our study was to evaluate the influence of the amount of myocardium subtended to an intermediate stenosis on FFR, especially in relation to quantitative coronary angiography.
Leone, A. M., De Caterina, A., Basile, E., Gardi, A., Laezza, D., Mazzari, M. A., Mongiardo, R., Kharbanda, R., Cuculi, F., Porto, I., Niccoli, G., Burzotta, F., Trani, C., Banning, A., Rebuzzi, A. G., Crea, F., Influence of the amount of myocardium subtended by a stenosis on fractional flow reserve, <<CIRCULATION. CARDIOVASCULAR INTERVENTIONS>>, 2013; 6 (1): 29-36. [doi:10.1161/CIRCINTERVENTIONS.112.971101] [http://hdl.handle.net/10807/53543]
Influence of the amount of myocardium subtended by a stenosis on fractional flow reserve
Leone, Antonio Maria;De Caterina, Alberto;Basile, Eloisa;Mazzari, Mario Attilio;Mongiardo, Rocco;Porto, Italo;Niccoli, Giampaolo;Burzotta, Francesco;Trani, Carlo;Rebuzzi, Antonio Giuseppe;Crea, Filippo
2013
Abstract
Fractional flow reserve (FFR) specifically relates to the severity of a stenosis to the mass of tissue to be perfused. Accordingly, the larger the territory to be perfused, the greater the flow and the pressure gradient induced by maximal hyperemia. Although this notion may be considered intuitive, its unequivocal demonstration is still lacking. The aim of our study was to evaluate the influence of the amount of myocardium subtended to an intermediate stenosis on FFR, especially in relation to quantitative coronary angiography.
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