Despite significant improvements in the prognosis of childhood acute lymphoblastic leukaemia (ALL), the risk of anthracycline-induced cardiovascular disease remains a major concern. This study was designed to investigate the role of the myocardial performance index (MPI) and serum concentrations of biomarkers (cTnT and NT-pro-BNP) in the early detection of subclinical anthracycline-induced functional alterations in children with ALL.

Ruggiero, A., De Rosa, G., Rizzo, D., Leo, A., Maurizi, P., De Nisco, A., Vendittelli, F., Zuppi, C., Mordente, A., Riccardi, R., Myocardial performance index and biochemical markers for early detection of doxorubicin-induced cardiotoxicity in children with acute lymphoblastic leukaemia, <<INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY>>, 2013; 18 (5): 927-933. [doi:10.1007/s10147-012-0458-9] [http://hdl.handle.net/10807/53458]

Myocardial performance index and biochemical markers for early detection of doxorubicin-induced cardiotoxicity in children with acute lymphoblastic leukaemia

Ruggiero, Antonio;De Rosa, Gabriella;Rizzo, Daniela;Maurizi, Palma;De Nisco, Alessia;Vendittelli, Francesca;Zuppi, Cecilia;Mordente, Alvaro;Riccardi, Riccardo
2013

Abstract

Despite significant improvements in the prognosis of childhood acute lymphoblastic leukaemia (ALL), the risk of anthracycline-induced cardiovascular disease remains a major concern. This study was designed to investigate the role of the myocardial performance index (MPI) and serum concentrations of biomarkers (cTnT and NT-pro-BNP) in the early detection of subclinical anthracycline-induced functional alterations in children with ALL.
Inglese
Ruggiero, A., De Rosa, G., Rizzo, D., Leo, A., Maurizi, P., De Nisco, A., Vendittelli, F., Zuppi, C., Mordente, A., Riccardi, R., Myocardial performance index and biochemical markers for early detection of doxorubicin-induced cardiotoxicity in children with acute lymphoblastic leukaemia, <<INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY>>, 2013; 18 (5): 927-933. [doi:10.1007/s10147-012-0458-9] [http://hdl.handle.net/10807/53458]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/53458
Citazioni
  • ???jsp.display-item.citation.pmc??? 21
  • Scopus 37
  • ???jsp.display-item.citation.isi??? 30
social impact