Cytarabine plays a pivotal role in the treatment of patients with acute myeloid leukemia (AML). Most centers use 7 to 10 days of cytarabine at a daily dose of 100 to 200 mg/m(2) for remission induction. Consensus has not been reached on the benefit of higher dosages of cytarabine.

Willemze, R., Suciu, S., Meloni, G., Labar, B., Marie, J., Halkes, C., Muus, P., Mistrik, M., Amadori, S., Specchia, G., Fabbiano, F., Nobile, F., Sborgia, M., Camera, A., Selleslag, D., Lefrère, F., Magro, D., Sica, S., Cantore, N., Beksac, M., Berneman, Z., Thomas, X., Melillo, L., Guimaraes, J., Leoni, P., Luppi, M., Mitra, M., Bron, D., Fillet, G., Marijt, E., Venditti, A., Hagemeijer, A., Mancini, M., Jansen, J., Cilloni, D., Meert, L., Fazi, P., Vignetti, M., Trisolini, S., Mandelli, F., De Witte, T., High-Dose Cytarabine in Induction Treatment Improves the Outcome of Adult Patients Younger Than Age 46 Years With Acute Myeloid Leukemia: Results of the EORTC-GIMEMA AML-12 Trial, <<Journal of clinical oncology : official journal of the American Society of Clinical Oncology>>, 2013; 32 (3): 219-228. [doi:10.1200/JCO.2013.51.8571] [http://hdl.handle.net/10807/50965]

High-Dose Cytarabine in Induction Treatment Improves the Outcome of Adult Patients Younger Than Age 46 Years With Acute Myeloid Leukemia: Results of the EORTC-GIMEMA AML-12 Trial

Sica, Simona;
2014

Abstract

Cytarabine plays a pivotal role in the treatment of patients with acute myeloid leukemia (AML). Most centers use 7 to 10 days of cytarabine at a daily dose of 100 to 200 mg/m(2) for remission induction. Consensus has not been reached on the benefit of higher dosages of cytarabine.
2014
Inglese
Willemze, R., Suciu, S., Meloni, G., Labar, B., Marie, J., Halkes, C., Muus, P., Mistrik, M., Amadori, S., Specchia, G., Fabbiano, F., Nobile, F., Sborgia, M., Camera, A., Selleslag, D., Lefrère, F., Magro, D., Sica, S., Cantore, N., Beksac, M., Berneman, Z., Thomas, X., Melillo, L., Guimaraes, J., Leoni, P., Luppi, M., Mitra, M., Bron, D., Fillet, G., Marijt, E., Venditti, A., Hagemeijer, A., Mancini, M., Jansen, J., Cilloni, D., Meert, L., Fazi, P., Vignetti, M., Trisolini, S., Mandelli, F., De Witte, T., High-Dose Cytarabine in Induction Treatment Improves the Outcome of Adult Patients Younger Than Age 46 Years With Acute Myeloid Leukemia: Results of the EORTC-GIMEMA AML-12 Trial, <<Journal of clinical oncology : official journal of the American Society of Clinical Oncology>>, 2013; 32 (3): 219-228. [doi:10.1200/JCO.2013.51.8571] [http://hdl.handle.net/10807/50965]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/50965
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