The development of new separation techniques and different mass spectrometry instrumental devices, as well as the great availability of specific reactants, offers ample choice to scientists for carrying out high-throughput proteomic studies and being competitive in the field today. However, the different options available often do not provide comparable results, which can be linked to factors such as the strategy adopted, the nature of the sample and the instrumental availability. In this critical review, the results obtained so far in the study of human saliva by different proteomic approaches will be compared and discussed.
Castagnola, M., Cabras, T., Iavarone, F., Fanali, C., Nemolato, S., Peluso, G., Bosello, S. L., Faa, G., Ferraccioli, G., Messana, I., The human salivary proteome: a critical overview of the results obtained by different proteomic platforms, <<EXPERT REVIEW OF PROTEOMICS>>, 2012; 9 (1): 33-46. [doi:10.1586/epr.11.77] [https://hdl.handle.net/10807/41199]
The human salivary proteome: a critical overview of the results obtained by different proteomic platforms
Castagnola, Massimo;Iavarone, Federica;Fanali, Chiara;Bosello, Silvia Laura;Ferraccioli, Gianfranco;
2012
Abstract
The development of new separation techniques and different mass spectrometry instrumental devices, as well as the great availability of specific reactants, offers ample choice to scientists for carrying out high-throughput proteomic studies and being competitive in the field today. However, the different options available often do not provide comparable results, which can be linked to factors such as the strategy adopted, the nature of the sample and the instrumental availability. In this critical review, the results obtained so far in the study of human saliva by different proteomic approaches will be compared and discussed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.