Although modern treatment strategies are highly eff ective in many cases of progressive chronic lymphocytic leukemia (CLL), a challenging subgroup of patients show poor response to standard regimens and a survival of less than 2 years [1]. In addition, a proportion of CLL ( ∼ 10%) undergoes transformation into diff use large B-cell lymphoma, an almost invariably lethal complication known as Richter syndrome (RS) [2,3].

De Paoli, L., Cerri, M., Monti, S., Rasi, S., Spina, V., Bruscaggin, A., Greco, M., Ciardullo, C., Famà, R., Cresta, S., Maffei, R., Ladetto, M., Martini, M., Laurenti, L., Forconi, F., Marasca, R., Larocca, L. M., Bertoni, F., Gaidano, G., Rossi, D., MGA, a suppressor of MYC, is recurrently inactivated in high risk chronic lymphocytic leukemia, <<LEUKEMIA & LYMPHOMA>>, 2012; (N/A): N/A-N/A. [doi:10.3109/10428194.2012.723706] [http://hdl.handle.net/10807/40283]

MGA, a suppressor of MYC, is recurrently inactivated in high risk chronic lymphocytic leukemia

Martini, Maurizio;Laurenti, Luca;Larocca, Luigi Maria;
2012

Abstract

Although modern treatment strategies are highly eff ective in many cases of progressive chronic lymphocytic leukemia (CLL), a challenging subgroup of patients show poor response to standard regimens and a survival of less than 2 years [1]. In addition, a proportion of CLL ( ∼ 10%) undergoes transformation into diff use large B-cell lymphoma, an almost invariably lethal complication known as Richter syndrome (RS) [2,3].
2012
Inglese
De Paoli, L., Cerri, M., Monti, S., Rasi, S., Spina, V., Bruscaggin, A., Greco, M., Ciardullo, C., Famà, R., Cresta, S., Maffei, R., Ladetto, M., Martini, M., Laurenti, L., Forconi, F., Marasca, R., Larocca, L. M., Bertoni, F., Gaidano, G., Rossi, D., MGA, a suppressor of MYC, is recurrently inactivated in high risk chronic lymphocytic leukemia, <<LEUKEMIA & LYMPHOMA>>, 2012; (N/A): N/A-N/A. [doi:10.3109/10428194.2012.723706] [http://hdl.handle.net/10807/40283]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/40283
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