Interindividual variability in response to aspirin has been popularized as 'resistance'. We hypothesized that faster recovery of platelet cyclooxygenase-1 activity may explain incomplete thromboxane (TX) inhibition during the 24-h dosing interval.

Rocca, B., Santilli, F., Pitocco, D., Mucci, L., Petrucci, G., Vitacolonna, E., Lattanzio, S., Mattoscio, D., Zaccardi, F., Liani, R., Vazzana, N., Del Ponte, A., Ferrante, E., Martini, F., Cardillo, C., Morosetti, R., Mirabella, M., Ghirlanda, G., Davì, G., Patrono, C., The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low-dose aspirin in patients with and without diabetes, <<JOURNAL OF THROMBOSIS AND HAEMOSTASIS>>, 2012; 10 (7): 1220-1230. [doi:10.1111/j.1538-7836.2012.04723.x] [http://hdl.handle.net/10807/40040]

The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low-dose aspirin in patients with and without diabetes

Rocca, Bianca;Santilli, Federico;Pitocco, Dario;Mucci, Luciana;Petrucci, Giovanna;Zaccardi, Francesco;Martini, Francesca;Cardillo, Carmine;Morosetti, Roberta;Mirabella, Massimiliano;Ghirlanda, Giovanni;Patrono, Carlo
2012

Abstract

Interindividual variability in response to aspirin has been popularized as 'resistance'. We hypothesized that faster recovery of platelet cyclooxygenase-1 activity may explain incomplete thromboxane (TX) inhibition during the 24-h dosing interval.
2012
Inglese
Rocca, B., Santilli, F., Pitocco, D., Mucci, L., Petrucci, G., Vitacolonna, E., Lattanzio, S., Mattoscio, D., Zaccardi, F., Liani, R., Vazzana, N., Del Ponte, A., Ferrante, E., Martini, F., Cardillo, C., Morosetti, R., Mirabella, M., Ghirlanda, G., Davì, G., Patrono, C., The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low-dose aspirin in patients with and without diabetes, <<JOURNAL OF THROMBOSIS AND HAEMOSTASIS>>, 2012; 10 (7): 1220-1230. [doi:10.1111/j.1538-7836.2012.04723.x] [http://hdl.handle.net/10807/40040]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/40040
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