Involvement of various gene mutations in hypertension have been already reported, including GST (detoxification Phase II enzymes), with contrasting results. This study analyzes a possible association between GSTM1-null and GSTT1-null polymorphisms and the hypertension status in a very old population (>80 years).
Capoluongo, E. D., Onder, G., Concolino, P., Russo, A., Santonocito, C., Bernabei, R., Zuppi, C., Ameglio, F., Landi, F. L., GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study), <<Clinica chimica acta; international journal of clinical chemistry>>, 2009; 399 (1-2): 92-96. [doi:10.1016/j.cca.2008.09.017] [http://hdl.handle.net/10807/33847]
GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study)
Capoluongo, Ettore Domenico;Onder, Graziano;Concolino, Paola;Russo, Andrea;Santonocito, Concetta;Bernabei, Roberto;Zuppi, Cecilia;Landi, Francesco Luigi
2009
Abstract
Involvement of various gene mutations in hypertension have been already reported, including GST (detoxification Phase II enzymes), with contrasting results. This study analyzes a possible association between GSTM1-null and GSTT1-null polymorphisms and the hypertension status in a very old population (>80 years).
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