An enzymatic hair extraction method is proposed for drug analysis. Pronase digestion of various aliquots of hair from a cocaine abuser was preceded by a 2-h incubation with a dithiothreitol solution. The extraction solution was tested to identify possible interferences in the radioimmunoassay and was compared with other hydrolysis methods to assess the results of extraction.
Offidani, C., Strano Rossi, S., Chiarotti, M., IMPROVED ENZYMATIC-HYDROLYSIS OF HAIR, <<FORENSIC SCIENCE INTERNATIONAL>>, 1993; 63 (Dicembre): 171-174. [doi:10.1016/0379-0738(93)90271-B] [http://hdl.handle.net/10807/30259]
IMPROVED ENZYMATIC-HYDROLYSIS OF HAIR
Strano Rossi, Sabina;Chiarotti, Marcello
1993
Abstract
An enzymatic hair extraction method is proposed for drug analysis. Pronase digestion of various aliquots of hair from a cocaine abuser was preceded by a 2-h incubation with a dithiothreitol solution. The extraction solution was tested to identify possible interferences in the radioimmunoassay and was compared with other hydrolysis methods to assess the results of extraction.
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