Here we briefly review from the literature the published cases of pre-surgical chemotherapy in medulloblastoma (MB)/PNET of childhood. We concluded that pre-surgical chemotherapy may be indicated for the following major reasons: 1) easier removal of the tumor; 2) early treatment of micrometastases; 3) all patients would be evaluable for sensitivity of the tumor to chemotherapy at diagnosis.
Mastrangelo, S., Tornesello, A., Piciacchia, D., Tortorolo, L., Riccardi, R., Di Rocco, C., Pre-surgical chemotherapy in medulloblastoma/PNET of childhood, <<ACTA MEDICA ROMANA>>, 1994; 32 (4): 492-496 [https://hdl.handle.net/10807/297631]
Pre-surgical chemotherapy in medulloblastoma/PNET of childhood
Mastrangelo, Stefano;Tornesello, Assunta;Tortorolo, Luca;Riccardi, Riccardo;
1994
Abstract
Here we briefly review from the literature the published cases of pre-surgical chemotherapy in medulloblastoma (MB)/PNET of childhood. We concluded that pre-surgical chemotherapy may be indicated for the following major reasons: 1) easier removal of the tumor; 2) early treatment of micrometastases; 3) all patients would be evaluable for sensitivity of the tumor to chemotherapy at diagnosis.
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