Punding, a peculiar stereotyped behavior characterized by intense fascination with complex, excessive, non-goal-oriented, repetitive activities, is a quite rare condition complicating Parkinson’s disease (PD). It is triggered by dopaminergic therapy and could have a strong impact on patient quality of life. No study has specifically investigated medical management of this condition, and only a few anecdotal reports have provided therapeutic hints. Given the suggested similarities to drug-induced dyskinesias, we have previously suggested a multistep algorithm for management of punding. We conducted a prospective open-label study on ten PD punders aimed at testing its validity. In two cases, reduction of levodopa therapy was efficacious; amantadine was effective in controlling punding in four cases; in the remaining cases, quetiapine was employed, with mild efficacy in two cases.

Fasano, A., Pettorruso, M., Ricciardi, L., Conte, G., Bentivoglio, A. R., PUNDING IN PARKINSON'S DISEASE: THE IMPACT OF PATIANT'S AWARENESS ON DIAGNOSIS, <<MOVEMENT DISORDERS>>, 2010; vol. 15;25(9) (Luglio): 1297-1299 [http://hdl.handle.net/10807/27993]

PUNDING IN PARKINSON'S DISEASE: THE IMPACT OF PATIANT'S AWARENESS ON DIAGNOSIS

Fasano, Alfonso;Pettorruso, Mauro;Conte, Gianluigi;Bentivoglio, Anna Rita
2010

Abstract

Punding, a peculiar stereotyped behavior characterized by intense fascination with complex, excessive, non-goal-oriented, repetitive activities, is a quite rare condition complicating Parkinson’s disease (PD). It is triggered by dopaminergic therapy and could have a strong impact on patient quality of life. No study has specifically investigated medical management of this condition, and only a few anecdotal reports have provided therapeutic hints. Given the suggested similarities to drug-induced dyskinesias, we have previously suggested a multistep algorithm for management of punding. We conducted a prospective open-label study on ten PD punders aimed at testing its validity. In two cases, reduction of levodopa therapy was efficacious; amantadine was effective in controlling punding in four cases; in the remaining cases, quetiapine was employed, with mild efficacy in two cases.
Inglese
Fasano, A., Pettorruso, M., Ricciardi, L., Conte, G., Bentivoglio, A. R., PUNDING IN PARKINSON'S DISEASE: THE IMPACT OF PATIANT'S AWARENESS ON DIAGNOSIS, <<MOVEMENT DISORDERS>>, 2010; vol. 15;25(9) (Luglio): 1297-1299 [http://hdl.handle.net/10807/27993]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/27993
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