Pure red cell aplasia (PRCA) is a rare complication of treatment with isoniazid mainly observed in adults. We report two siblings who had anemia caused Ly PRCA during administration of isoniazid. On discontinuation of isoniazid, the anemia resolved rapidly. PRCA should be considered as a possible cause of unexplained anemia during isoniazid therapy in children.
Marseglia, G. L., Locatelli, F., Isoniazid-induced pure red cell aplasia in two siblings, <<THE JOURNAL OF PEDIATRICS>>, 1998; 132 (5): 898-900. [doi:10.1016/s0022-3476(98)70330-0] [https://hdl.handle.net/10807/264717]
Isoniazid-induced pure red cell aplasia in two siblings
Locatelli, Franco
1998
Abstract
Pure red cell aplasia (PRCA) is a rare complication of treatment with isoniazid mainly observed in adults. We report two siblings who had anemia caused Ly PRCA during administration of isoniazid. On discontinuation of isoniazid, the anemia resolved rapidly. PRCA should be considered as a possible cause of unexplained anemia during isoniazid therapy in children.
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