: Hematological toxicity following Chimeric Antigen Receptor-T therapy in a patient with a prior allogeneic stem cell transplantation was resolved by the infusion of unselected donor-derived stem cell boost. Due to the donor's lymphocytes, the patient experienced a well-controlled flare-up of acute graft versus host disease.
Galli, E., Limongiello, M. A., Metafuni, E., Giammarco, S., Fresa, A., Piccirillo, N., Bianchi, M., Laurenti, L., Sora', F., Chiusolo, P., Sica, S., Unselected donor-derived hematopoietic stem cells boost for Chimeric Antigen Receptor T-cell associated hematotoxicity, <<AMERICAN JOURNAL OF HEMATOLOGY>>, 2024; (Jan): N/A-N/A. [doi:10.1002/ajh.27208] [https://hdl.handle.net/10807/262736]
Unselected donor-derived hematopoietic stem cells boost for Chimeric Antigen Receptor T-cell associated hematotoxicity
Galli, Eugenio;Metafuni, Elisabetta;Fresa, Alberto;Piccirillo, Nicola;Bianchi, Maria;Laurenti, Luca;Sora', Federica;Chiusolo, Patrizia;Sica, Simona
2024
Abstract
: Hematological toxicity following Chimeric Antigen Receptor-T therapy in a patient with a prior allogeneic stem cell transplantation was resolved by the infusion of unselected donor-derived stem cell boost. Due to the donor's lymphocytes, the patient experienced a well-controlled flare-up of acute graft versus host disease.
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