In Hodgkin's lymphoma (HL), the production of cytokines by Reed-Sternberg cells and the surrounding tissue is thought to contribute to the biology of the disease. Cytokine expression can be altered by common single nucleotide polymorphisms (SNPs) in the 5'-promoter regions.
Hohaus, S., Giachelia, M., Di Febo, A., Martini, M., Massini, G., Vannata, B., D'Alo', F., Guidi, F., Greco, M. A., Pierconti, F., Larocca, L. M., Voso, M. T., Leone, G., Polymorphism in cytokine genes as prognostic markers in Hodgkin's lymphoma, <<ANNALS OF ONCOLOGY>>, 2007; 18 (8): 1376-1381. [doi:10.1093/annonc/mdm132] [http://hdl.handle.net/10807/26206]
Polymorphism in cytokine genes as prognostic markers in Hodgkin's lymphoma
Hohaus, Stefan;Di Febo, Annalaura;Martini, Maurizio;Massini, Giuseppina;D'Alo', Francesco;Guidi, Francesco;Pierconti, Francesco;Larocca, Luigi Maria;Voso, Maria Teresa;
2007
Abstract
In Hodgkin's lymphoma (HL), the production of cytokines by Reed-Sternberg cells and the surrounding tissue is thought to contribute to the biology of the disease. Cytokine expression can be altered by common single nucleotide polymorphisms (SNPs) in the 5'-promoter regions.
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