This work studies the distribution of cocaine and heroin metabolites in hair and urine of living polidrug abusers. Cocaine, benzoylecgonine (BEG), ecgonine methyl ester (EME), morphine, codeine and 6-monoacetylmorphine (6-MAM) were simultaneously extracted and analyzed by GC/MS in SIM mode. The results obtained show a different distribution of heroin and cocaine metabolites in urine and hair. In urine, we generally find BEG and EME for cocaine abuse, and morphine for heroin abuse. In hair, we detect cocaine and MAM as major metabolites for cocaine and heroin abuse, respectively. © 1995.

Barrera, A. M. B., Strano Rossi, S., Hair and urine analysis: relative distribution of drugs and their metabolites, <<FORENSIC SCIENCE INTERNATIONAL>>, 1995; 70 (1-3): 203-210. [doi:10.1016/0379-0738(94)01614-B] [https://hdl.handle.net/10807/256901]

Hair and urine analysis: relative distribution of drugs and their metabolites

Strano Rossi, Sabina
Ultimo
Conceptualization
1995

Abstract

This work studies the distribution of cocaine and heroin metabolites in hair and urine of living polidrug abusers. Cocaine, benzoylecgonine (BEG), ecgonine methyl ester (EME), morphine, codeine and 6-monoacetylmorphine (6-MAM) were simultaneously extracted and analyzed by GC/MS in SIM mode. The results obtained show a different distribution of heroin and cocaine metabolites in urine and hair. In urine, we generally find BEG and EME for cocaine abuse, and morphine for heroin abuse. In hair, we detect cocaine and MAM as major metabolites for cocaine and heroin abuse, respectively. © 1995.
1995
Inglese
Barrera, A. M. B., Strano Rossi, S., Hair and urine analysis: relative distribution of drugs and their metabolites, <<FORENSIC SCIENCE INTERNATIONAL>>, 1995; 70 (1-3): 203-210. [doi:10.1016/0379-0738(94)01614-B] [https://hdl.handle.net/10807/256901]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/256901
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