Optic pathway gliomas (OPG) are a common cancer in children with neurofibromatosis type 1.OPGs can cause clinical symptoms such as reduction of visual acuity, alterations of the visual field, pallor of the optical papilla, strabismus, endocrinological alterations up to diencephalic syndrome.The current guidelines provide for wait and see as the main approach if the tumor is not causing visual deterioration and adapting treatment only in the event of significant impairment of the visual function. Therefore, it is essential to early detect the visual deterioration changes as well as the identification of children eligible for treatment. © 2020 This is an Open Access article licensed under a Creative Commons license: Attribution 4.0 International (CC-BY).
Attina', G., Maurizi, P., Triarico, S., Capozza, M. A., Romano, A., Mastrangelo, S., Ruggiero, A., Management of Children with Optic Gliomas and Neurofibromatosis Type 1, <<BIOMEDICAL & PHARMACOLOGY JOURNAL>>, 2020; 13 (4): 1601-1606. [doi:10.13005/bpj/2035] [https://hdl.handle.net/10807/237016]
Management of Children with Optic Gliomas and Neurofibromatosis Type 1
Attina', Giorgio;Maurizi, Palma;Mastrangelo, Stefano;Ruggiero, Antonio
2020
Abstract
Optic pathway gliomas (OPG) are a common cancer in children with neurofibromatosis type 1.OPGs can cause clinical symptoms such as reduction of visual acuity, alterations of the visual field, pallor of the optical papilla, strabismus, endocrinological alterations up to diencephalic syndrome.The current guidelines provide for wait and see as the main approach if the tumor is not causing visual deterioration and adapting treatment only in the event of significant impairment of the visual function. Therefore, it is essential to early detect the visual deterioration changes as well as the identification of children eligible for treatment. © 2020 This is an Open Access article licensed under a Creative Commons license: Attribution 4.0 International (CC-BY).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.