Gut microbiota (GM) composition and its imbalance are crucial in the pathogenesis of several diseases, mainly those affecting the gastrointestinal tract. Colon diverticulosis and its clinical manifestations (diverticular disease, DD) are among the most common digestive disorders in developed countries. In recent literature, the role of GM imbalance in the onset of the different manifestations within the clinical spectrum of DD has been highlighted. This narrative review aims to summarize and critically analyze the current knowledge on GM dysbiosis in diverticulosis and DD by comparing the available data with those found in inflammatory bowel disease (IBD). The rationale for using probiotics to rebalance dysbiosis in DD is also discussed.

Tursi, A., Papa, V., Lopetuso, L. R., Settanni, C. R., Gasbarrini, A., Papa, A., Microbiota Composition in Diverticular Disease: Implications for Therapy, <<INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES>>, 2022; 23 (23): 14799-N/A. [doi:10.3390/ijms232314799] [https://hdl.handle.net/10807/231823]

Microbiota Composition in Diverticular Disease: Implications for Therapy

Tursi, Antonio;Papa, Valerio;Lopetuso, Loris Riccardo;Settanni, Carlo Romano;Gasbarrini, Antonio;Papa, Alfredo
Ultimo
2022

Abstract

Gut microbiota (GM) composition and its imbalance are crucial in the pathogenesis of several diseases, mainly those affecting the gastrointestinal tract. Colon diverticulosis and its clinical manifestations (diverticular disease, DD) are among the most common digestive disorders in developed countries. In recent literature, the role of GM imbalance in the onset of the different manifestations within the clinical spectrum of DD has been highlighted. This narrative review aims to summarize and critically analyze the current knowledge on GM dysbiosis in diverticulosis and DD by comparing the available data with those found in inflammatory bowel disease (IBD). The rationale for using probiotics to rebalance dysbiosis in DD is also discussed.
2022
Inglese
Tursi, A., Papa, V., Lopetuso, L. R., Settanni, C. R., Gasbarrini, A., Papa, A., Microbiota Composition in Diverticular Disease: Implications for Therapy, <<INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES>>, 2022; 23 (23): 14799-N/A. [doi:10.3390/ijms232314799] [https://hdl.handle.net/10807/231823]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/231823
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