Background: Neuropsychological testing plays a cardinal role in the diagnosis and monitoring of Alzheimer's disease. A major concern is represented by the heterogeneity of the neuropsychological batteries currently adopted in memory clinics and healthcare centers. The current study aimed to solve this issue. Methods: Following the initiative of the University of Washington's National Alzheimer's Coordinating Center (NACC), we presented the Italian adaptation of the Neuropsychological Test Battery of the Uniform Data Set (I-UDSNB). We collected data from 433 healthy Italian individuals and employed regression models to evaluate the impact of demographic variables on the performance, deriving the reference norms. Results: Higher education and lower age were associated with a better performance in the majority of tests, while sex affected only fluency tests and Digit Span Forward. Conclusions: The I-UDSNB offers a valuable and harmonized tool for neuropsychological testing in Italy, to be used in clinical and research settings.
Conca, F., Esposito, V., Rundo, F., Quaranta, D., Muscio, C., Manenti, R., Caruso, G., Lucca, U., Galbussera, A. A., Di Tella, S., Baglio, F., L'Abbate, F., Canu, E., Catania, V., Filippi, M., Mattavelli, G., Poletti, B., Silani, V., Lodi, R., De Matteis, M., Stanzani Maserati, M., Arighi, A., Rotondo, E., Tanzilli, A., Pace, A., Garramone, F., Cavaliere, C., Pardini, M., Rizzetto, C., Sorbi, S., Perri, R., Tiraboschi, P., Canessa, N., Cotelli, M., Ferri, R., Weintraub, S., Marra, C., Tagliavini, F., Catricalà, E., Cappa, S. F., Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data, <<ALZHEIMER'S RESEARCH & THERAPY>>, 2022; 14 (113): 1-11. [doi:10.1186/s13195-022-01056-x] [https://hdl.handle.net/10807/224712]
Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data
Quaranta, Davide;Manenti, Rosa;Di Tella, Sonia;Cotelli, Maria;Marra, Camillo;Cappa, Stefano Francesco
2022
Abstract
Background: Neuropsychological testing plays a cardinal role in the diagnosis and monitoring of Alzheimer's disease. A major concern is represented by the heterogeneity of the neuropsychological batteries currently adopted in memory clinics and healthcare centers. The current study aimed to solve this issue. Methods: Following the initiative of the University of Washington's National Alzheimer's Coordinating Center (NACC), we presented the Italian adaptation of the Neuropsychological Test Battery of the Uniform Data Set (I-UDSNB). We collected data from 433 healthy Italian individuals and employed regression models to evaluate the impact of demographic variables on the performance, deriving the reference norms. Results: Higher education and lower age were associated with a better performance in the majority of tests, while sex affected only fluency tests and Digit Span Forward. Conclusions: The I-UDSNB offers a valuable and harmonized tool for neuropsychological testing in Italy, to be used in clinical and research settings.
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