The implementation of cancer molecular characterization in clinical practice has improved prognostic re-definition, extending the eligibility to a continuously increasing number of targeted treatments. Broad molecular profiling technologies better than organ-based approaches are believed to serve such dynamic purposes. We here present the workflow our institution adopted to run a comprehensive cancer genome profiling in clinical practice. This article describes the workflow designed to make a comprehensive cancer genome profiling program feasible and sustainable in a large-volume referral hospital. Keywords: bioinformatics; cancer; comprehensive cancer genome profiling; genomics; target therapy.

Nero, C., Duranti, S., Giacomini, F., Minucci, A., Giacò, L., Piermattei, A., Genuardi, M., Pasciuto, T., Urbani, A., Daniele, G., Lorusso, D., Pignataro, R., Tortora, G., Normanno, N., Scambia, G., Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center, <<JOURNAL OF PERSONALIZED MEDICINE>>, 2022; 2022 (10): 1746-1746. [doi:10.3390/jpm12101746]

Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center

Nero, C;Giacomini, F;Minucci, A;Piermattei, A;Genuardi, M;Pasciuto, T;Daniele, G;Pignataro, R;Tortora, G;Scambia, G.
2022

Abstract

The implementation of cancer molecular characterization in clinical practice has improved prognostic re-definition, extending the eligibility to a continuously increasing number of targeted treatments. Broad molecular profiling technologies better than organ-based approaches are believed to serve such dynamic purposes. We here present the workflow our institution adopted to run a comprehensive cancer genome profiling in clinical practice. This article describes the workflow designed to make a comprehensive cancer genome profiling program feasible and sustainable in a large-volume referral hospital. Keywords: bioinformatics; cancer; comprehensive cancer genome profiling; genomics; target therapy.
Inglese
Nero, C., Duranti, S., Giacomini, F., Minucci, A., Giacò, L., Piermattei, A., Genuardi, M., Pasciuto, T., Urbani, A., Daniele, G., Lorusso, D., Pignataro, R., Tortora, G., Normanno, N., Scambia, G., Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center, <<JOURNAL OF PERSONALIZED MEDICINE>>, 2022; 2022 (10): 1746-1746. [doi:10.3390/jpm12101746]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/219745
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