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Gemcitabine (2′-2′-difluorodeoxycytidine) is a well-known cytotoxic drug and a potent radio-enhancer. We herein report the in vitro evidence of its activity, and the clinical experiences when this drug is administered concurrently with radiation. The phase I-II trials are analyzed, focusing on the recent ability to deliver irradiation with low incidence of side effects. © 2006 Oxford University Press.

Trodella, L., D'Angelillo, R. M., Ramella, S., Cellini, F., Ciresa, M., Cesario, A., Granone, P., Chemo-radiotherapy in non-small cell lung cancer: The role of gemcitabine, <<ANNALS OF ONCOLOGY>>, 2006; 17 (5): v52-v54. [doi:10.1093/annonc/mdj950] [http://hdl.handle.net/10807/204839]

Chemo-radiotherapy in non-small cell lung cancer: The role of gemcitabine

Cellini, Francesco;Cesario, Alfredo;Granone, Pierluigi
2006

Abstract

Gemcitabine (2′-2′-difluorodeoxycytidine) is a well-known cytotoxic drug and a potent radio-enhancer. We herein report the in vitro evidence of its activity, and the clinical experiences when this drug is administered concurrently with radiation. The phase I-II trials are analyzed, focusing on the recent ability to deliver irradiation with low incidence of side effects. © 2006 Oxford University Press.
2006
Inglese
ANNALS OF ONCOLOGY
Trodella, L., D'Angelillo, R. M., Ramella, S., Cellini, F., Ciresa, M., Cesario, A., Granone, P., Chemo-radiotherapy in non-small cell lung cancer: The role of gemcitabine, <<ANNALS OF ONCOLOGY>>, 2006; 17 (5): v52-v54. [doi:10.1093/annonc/mdj950] [http://hdl.handle.net/10807/204839]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/204839
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