Teeth extractions before or after radiotherapy (RT) could be procedures at high risk for osteoradionecrosis (ORN) onset. This systematic review was performed to investigate the ORN incidence following teeth extractions during and after RT for head and neck (H&N) cancer and to evaluate any other possible risk factor. Methods: This systematic review was conducted according to PRISMA protocol, and the PROSPERO registration number was CRD42018079986. An electronic search was performed on the following search engines: PubMed, Scopus, and Web of Science. A cumulative meta‐analysis was performed. Results: Two thousand two hundred and eighty‐one records were screened, and nine were finally included. This systematic review revealed an ORN incidence of 5.8% (41 patients out of 462, 95% CI = 2.3–9.4); 3 ORN developed in the maxilla. No other clinical risk factors were detected. Conclusion: Post‐RT teeth extractions represent a major risk factor for ORN development, especially in the mandible, with a diminishing trend in the last years. Further research on other possible risk factors might improve this evidence.

Lajolo, C., Rupe, C., Gioco, G., Troiano, G., Patini, R., Petruzzi, M., Micciche', F., Giuliani, M., Osteoradionecrosis of the jaws due to teeth extractions during and after radiotherapy: A systematic review, <<CANCERS>>, 2022; 13 (22): 5798-5798. [doi:10.3390/cancers13225798] [http://hdl.handle.net/10807/196368]

Osteoradionecrosis of the jaws due to teeth extractions during and after radiotherapy: A systematic review

Lajolo, Carlo
Primo
;
Gioco, Gioele
Secondo
;
Patini, Romeo;Micciche', Francesco
Penultimo
;
2021

Abstract

Teeth extractions before or after radiotherapy (RT) could be procedures at high risk for osteoradionecrosis (ORN) onset. This systematic review was performed to investigate the ORN incidence following teeth extractions during and after RT for head and neck (H&N) cancer and to evaluate any other possible risk factor. Methods: This systematic review was conducted according to PRISMA protocol, and the PROSPERO registration number was CRD42018079986. An electronic search was performed on the following search engines: PubMed, Scopus, and Web of Science. A cumulative meta‐analysis was performed. Results: Two thousand two hundred and eighty‐one records were screened, and nine were finally included. This systematic review revealed an ORN incidence of 5.8% (41 patients out of 462, 95% CI = 2.3–9.4); 3 ORN developed in the maxilla. No other clinical risk factors were detected. Conclusion: Post‐RT teeth extractions represent a major risk factor for ORN development, especially in the mandible, with a diminishing trend in the last years. Further research on other possible risk factors might improve this evidence.
2021
Inglese
Lajolo, C., Rupe, C., Gioco, G., Troiano, G., Patini, R., Petruzzi, M., Micciche', F., Giuliani, M., Osteoradionecrosis of the jaws due to teeth extractions during and after radiotherapy: A systematic review, <<CANCERS>>, 2022; 13 (22): 5798-5798. [doi:10.3390/cancers13225798] [http://hdl.handle.net/10807/196368]
File in questo prodotto:
File Dimensione Formato  
Pubblicazione_PATINI.pdf

accesso aperto

Tipologia file ?: Versione Editoriale (PDF)
Licenza: Creative commons
Dimensione 718.09 kB
Formato Adobe PDF
718.09 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/196368
Citazioni
  • ???jsp.display-item.citation.pmc??? 8
  • Scopus 14
  • ???jsp.display-item.citation.isi??? 14
social impact