Stevens-Johnson syndrome (SJS) is a severe cutaneous eruption that most often appears as an adverse reaction to medication. In this report, we present two children with brain tumour who developed SJS while receiving cranial irradiation and anticonvulsant therapy with phenobarbital. Concomitant application of these two therapies may play an important role in the occurrence of the disease
Ruggiero, A., Buonuomo, P. S., Maurizi, P., Cefalo, M. P., Corsello, M., Riccardi, R., Stevens-Johnson syndrome in children receiving phenobarbital therapy and cranial radiotherapy., <<JOURNAL OF NEURO-ONCOLOGY>>, 2007; 85 (2): 213-215. [doi:10.1007/s11060-007-9399-y] [http://hdl.handle.net/10807/19032]
Stevens-Johnson syndrome in children receiving phenobarbital therapy and cranial radiotherapy.
Ruggiero, Antonio;Buonuomo, Paola Sabrina;Maurizi, Palma;Corsello, Mirta;Riccardi, Riccardo
2007
Abstract
Stevens-Johnson syndrome (SJS) is a severe cutaneous eruption that most often appears as an adverse reaction to medication. In this report, we present two children with brain tumour who developed SJS while receiving cranial irradiation and anticonvulsant therapy with phenobarbital. Concomitant application of these two therapies may play an important role in the occurrence of the disease
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