We explored the association between cognitive reserve (CR) and Parkinson' s disease (PD) related cognitive deterioration. Forty PD patients and 12 matchedhealthy controls (HC) were enrolled. The PD group was balanced for the presence/absence of cognitive impairment All participants underwent MOCA. CR was measured by the Brief Intelligence Test, and a new comprehensive tool, named Cognitive Reserve Test (CoRe-T), including sections on leisure activities and creativity. Participants with higher CR obtained a better MOCA score irrespective of the group they belonged to. At the same time, irrespective of the CR level, the performance of the HC group was always better in comparison to the PD group. Within the PD group, a higher frequency of leisure activities was associated to be cognitively unimpaired, independently by the severity of motor symptoms and age. CR could help to cope with PD-related cognitive decline. Its multidimensional nature could have important applications in prevention and rehabilitation interventions.

Ciccarelli, N., Colombo, B., Pepe, F., Magni, E., Antonietti, A., Silveri, M. C., Cognitive reserve: a multidimensional protective factor in Parkinson’s disease related cognitive impairment, <<NEUROPSYCHOLOGY, DEVELOPMENT, AND COGNITION. SECTION B, AGING, NEUROPSYCHOLOGY AND COGNITION>>, 2022; 29 (4): 687-702. [doi:10.1080/13825585.2021.1892026] [https://hdl.handle.net/10807/173845]

Cognitive reserve: a multidimensional protective factor in Parkinson’s disease related cognitive impairment

Ciccarelli, Nicoletta
;
Magni, Eugenio;Antonietti, Alessandro;Silveri, Maria Caterina
2021

Abstract

We explored the association between cognitive reserve (CR) and Parkinson' s disease (PD) related cognitive deterioration. Forty PD patients and 12 matchedhealthy controls (HC) were enrolled. The PD group was balanced for the presence/absence of cognitive impairment All participants underwent MOCA. CR was measured by the Brief Intelligence Test, and a new comprehensive tool, named Cognitive Reserve Test (CoRe-T), including sections on leisure activities and creativity. Participants with higher CR obtained a better MOCA score irrespective of the group they belonged to. At the same time, irrespective of the CR level, the performance of the HC group was always better in comparison to the PD group. Within the PD group, a higher frequency of leisure activities was associated to be cognitively unimpaired, independently by the severity of motor symptoms and age. CR could help to cope with PD-related cognitive decline. Its multidimensional nature could have important applications in prevention and rehabilitation interventions.
2021
Inglese
Ciccarelli, N., Colombo, B., Pepe, F., Magni, E., Antonietti, A., Silveri, M. C., Cognitive reserve: a multidimensional protective factor in Parkinson’s disease related cognitive impairment, <<NEUROPSYCHOLOGY, DEVELOPMENT, AND COGNITION. SECTION B, AGING, NEUROPSYCHOLOGY AND COGNITION>>, 2022; 29 (4): 687-702. [doi:10.1080/13825585.2021.1892026] [https://hdl.handle.net/10807/173845]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/173845
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