This study was designed to evaluate if patients in whom in-stent restenosis developed had an higher risk of early venous graft failure compared with normal patients. METHODS: The study cohort comprised 120 patients (60 with previous in-stent restenosis and 60 controls) who received a total of 165 complementary venous grafts on the circumflex or right coronary artery system (84 in the restenosis group and 81 in the control group). All patients were prospectively followed-up and underwent reangiography at 5-years follow-up. RESULTS: In the restenosis group, 28 venous grafts (33.%) were perfectly patent, 10 showed major irregularities, and 46 were occluded. In the control patients, 50 grafts (61.7%) were perfectly patent (p < 0.001 compared with the restenosis series), 12 showed major irregularities (p = .74), and 19 were occluded (p < 0.0001). In contrast, the 5-year outcome of internal thoracic artery grafts was not affected by history of in-stent restenosis. CONCLUSIONS: Patients who developed in-stent restenosis have an higher risk of early venous graft failure compared with the control patients. Arterial grafts should probably be preferred in these patients.

Gaudino, M. F. L., Luciani, N., Glieca, F., Cellini, C., Pragliola, C., Trani, C., Burzotta, F., Schiavoni, G., Anselmi, A., Possati, G. F., Patients with in-stent restenosis have an increased risk of mid-term venous graft failure., <<ANNALS OF THORACIC SURGERY>>, 2006; (82): 802-804 [http://hdl.handle.net/10807/157276]

Patients with in-stent restenosis have an increased risk of mid-term venous graft failure.

Gaudino, Mario Fulvio Luigi;Luciani, Nicola;Glieca, Franco;Cellini, Carlo;Pragliola, Claudio;Trani, Carlo;Burzotta, Francesco;Schiavoni, Giovanni;Possati, Gian Federico
2006

Abstract

This study was designed to evaluate if patients in whom in-stent restenosis developed had an higher risk of early venous graft failure compared with normal patients. METHODS: The study cohort comprised 120 patients (60 with previous in-stent restenosis and 60 controls) who received a total of 165 complementary venous grafts on the circumflex or right coronary artery system (84 in the restenosis group and 81 in the control group). All patients were prospectively followed-up and underwent reangiography at 5-years follow-up. RESULTS: In the restenosis group, 28 venous grafts (33.%) were perfectly patent, 10 showed major irregularities, and 46 were occluded. In the control patients, 50 grafts (61.7%) were perfectly patent (p < 0.001 compared with the restenosis series), 12 showed major irregularities (p = .74), and 19 were occluded (p < 0.0001). In contrast, the 5-year outcome of internal thoracic artery grafts was not affected by history of in-stent restenosis. CONCLUSIONS: Patients who developed in-stent restenosis have an higher risk of early venous graft failure compared with the control patients. Arterial grafts should probably be preferred in these patients.
Inglese
Gaudino, M. F. L., Luciani, N., Glieca, F., Cellini, C., Pragliola, C., Trani, C., Burzotta, F., Schiavoni, G., Anselmi, A., Possati, G. F., Patients with in-stent restenosis have an increased risk of mid-term venous graft failure., <<ANNALS OF THORACIC SURGERY>>, 2006; (82): 802-804 [http://hdl.handle.net/10807/157276]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/157276
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