A fatality due to ingestion of flurazepam is reported. Flurazepam is a benzodiazepine, a widely prescribed hypnotic drug for use in sleep disorders. There are only few documented reports of the disposition of flurazepam in deaths due to overdose. A 68-year-old woman was found deceased at home with no evidence of trauma or asphyxia. Toxicologic analyses were performed and drug levels measured by means of gas chromatography coupled to mass spectrometry. The flurazepam concentration in each specimen was as follows: heart blood 2.8 microg/mL, bile 323 microg/mL, and urine 172 microg/mL. Presence of flurazepam into gastric content was observed too. Based on the autopsy findings, patient history, and toxicologic results, the cause of death was determined to be acute intoxication of flurazepam and the manner, suicide.

Martello, S., Oliva, A., De Giorgio, F., Chiarotti, M., Acute flurazepam intoxication: a case report, <<THE AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY>>, 2006; 2006 (Marzo): 55-57 [http://hdl.handle.net/10807/13453]

Acute flurazepam intoxication: a case report

Martello, Simona;Oliva, Antonio;De Giorgio, Fabio;Chiarotti, Marcello
2006

Abstract

A fatality due to ingestion of flurazepam is reported. Flurazepam is a benzodiazepine, a widely prescribed hypnotic drug for use in sleep disorders. There are only few documented reports of the disposition of flurazepam in deaths due to overdose. A 68-year-old woman was found deceased at home with no evidence of trauma or asphyxia. Toxicologic analyses were performed and drug levels measured by means of gas chromatography coupled to mass spectrometry. The flurazepam concentration in each specimen was as follows: heart blood 2.8 microg/mL, bile 323 microg/mL, and urine 172 microg/mL. Presence of flurazepam into gastric content was observed too. Based on the autopsy findings, patient history, and toxicologic results, the cause of death was determined to be acute intoxication of flurazepam and the manner, suicide.
Inglese
Martello, S., Oliva, A., De Giorgio, F., Chiarotti, M., Acute flurazepam intoxication: a case report, <<THE AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY>>, 2006; 2006 (Marzo): 55-57 [http://hdl.handle.net/10807/13453]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/13453
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact