POEMS syndrome is a rare paraneoplastic condition, with a poorly understood pathogenesis. High dose chemotherapy followed by autologous stem cell transplantation (ASCT) has been reported to be an effective therapeutic option for patients with good performance status. Here, we review the role of ASCT for POEMS syndrome and discuss indications together with advantages and disadvantages, and related issues such lenalidomide given before or after ASCT, VEGF levels as a marker of disease, and different regimens for stem cell mobilization.

Autore, F., Innocenti, I., Luigetti, M., Piccirillo, N., Sorà, F., Chiusolo, P., Sica, S., Bacigalupo, A., Laurenti, L., Autologous peripheral blood stem cell transplantation and the role of lenalidomide in patients affected by poems syndrome, <<HEMATOLOGICAL ONCOLOGY>>, 2017; 36 (2): 392-398. [doi:10.1002/hon.2478] [http://hdl.handle.net/10807/117522]

Autologous peripheral blood stem cell transplantation and the role of lenalidomide in patients affected by poems syndrome

Autore, Francesco;Innocenti, Idanna;Luigetti, Marco;Piccirillo, Nicola;Sorà, Federica;Chiusolo, Patrizia;Sica, Simona;Bacigalupo, Andrea;Laurenti, Luca
2017

Abstract

POEMS syndrome is a rare paraneoplastic condition, with a poorly understood pathogenesis. High dose chemotherapy followed by autologous stem cell transplantation (ASCT) has been reported to be an effective therapeutic option for patients with good performance status. Here, we review the role of ASCT for POEMS syndrome and discuss indications together with advantages and disadvantages, and related issues such lenalidomide given before or after ASCT, VEGF levels as a marker of disease, and different regimens for stem cell mobilization.
Inglese
http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1099-1069
Autore, F., Innocenti, I., Luigetti, M., Piccirillo, N., Sorà, F., Chiusolo, P., Sica, S., Bacigalupo, A., Laurenti, L., Autologous peripheral blood stem cell transplantation and the role of lenalidomide in patients affected by poems syndrome, <>, 2017; 36 (2): 392-398. [doi:10.1002/hon.2478] [http://hdl.handle.net/10807/117522]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/117522
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 5
  • ???jsp.display-item.citation.isi??? 5
social impact