Pharmacologic treatment of myocardial ischemia in patients with chronic stable angina (CSA) is mainly based on heart rate lowering drugs and vasodilator agents. Other drugs are available, however, that act by some peculiar mechanism (ranolazine, trimetazidine) and may add potential anti-ischemic and anti-anginal effects to standard therapeutic mechanisms. While anti-ischemic agents are crucial for controlling angina symptoms and improving quality of life, whether myocardial ischemia portends an ominous prognosis and its suppression improves clinical outcome in CSA patients remain debated issues.

Lanza, G. A., Crea, F., Overview of Management of Myocardial Ischemia: a Mechanistic-Based Approach, <<CARDIOVASCULAR DRUGS AND THERAPY>>, 2016; 30 (4): 341-349. [doi:10.1007/s10557-016-6662-5] [http://hdl.handle.net/10807/98559]

Overview of Management of Myocardial Ischemia: a Mechanistic-Based Approach

Lanza, Gaetano Antonio
;
Crea, Filippo
Ultimo
2016

Abstract

Pharmacologic treatment of myocardial ischemia in patients with chronic stable angina (CSA) is mainly based on heart rate lowering drugs and vasodilator agents. Other drugs are available, however, that act by some peculiar mechanism (ranolazine, trimetazidine) and may add potential anti-ischemic and anti-anginal effects to standard therapeutic mechanisms. While anti-ischemic agents are crucial for controlling angina symptoms and improving quality of life, whether myocardial ischemia portends an ominous prognosis and its suppression improves clinical outcome in CSA patients remain debated issues.
Inglese
Lanza, G. A., Crea, F., Overview of Management of Myocardial Ischemia: a Mechanistic-Based Approach, <<CARDIOVASCULAR DRUGS AND THERAPY>>, 2016; 30 (4): 341-349. [doi:10.1007/s10557-016-6662-5] [http://hdl.handle.net/10807/98559]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/98559
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