In industrialized countries, overweight and obesity account for approximately 13.8% and 24.9% of the kidney disease observed in men and women, respectively. Moreover, obesity-associated glomerulopathy is now considered as "an emerging epidemic." Kidney function can be negatively impacted by obesity through several mechanisms, either direct or indirect. While it is well established that obesity represents the leading risk factor for type 2 diabetes and hypertension, awareness that obesity is associated with direct kidney damage independently of hypertension and diabetes is still not widespread. In this paper we will discuss the emerging role of adipose tissue, particularly in the visceral depot, in obesity-induced chronic kidney damage.

Mascali, A., Franzese, O., Nistico', S., Campia, U., Lauro, D., Cardillo, C., Di Daniele, N., Tesauro, M., Obesity and kidney disease: Beyond the hyperfiltration, <<INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY>>, 2016; 29 (3): 354-363. [doi:10.1177/0394632016643550] [http://hdl.handle.net/10807/94730]

Obesity and kidney disease: Beyond the hyperfiltration

Nistico', Salvatore
;
Cardillo, Carmine;
2016

Abstract

In industrialized countries, overweight and obesity account for approximately 13.8% and 24.9% of the kidney disease observed in men and women, respectively. Moreover, obesity-associated glomerulopathy is now considered as "an emerging epidemic." Kidney function can be negatively impacted by obesity through several mechanisms, either direct or indirect. While it is well established that obesity represents the leading risk factor for type 2 diabetes and hypertension, awareness that obesity is associated with direct kidney damage independently of hypertension and diabetes is still not widespread. In this paper we will discuss the emerging role of adipose tissue, particularly in the visceral depot, in obesity-induced chronic kidney damage.
Inglese
Mascali, A., Franzese, O., Nistico', S., Campia, U., Lauro, D., Cardillo, C., Di Daniele, N., Tesauro, M., Obesity and kidney disease: Beyond the hyperfiltration, <<INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY>>, 2016; 29 (3): 354-363. [doi:10.1177/0394632016643550] [http://hdl.handle.net/10807/94730]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/94730
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