Here we present a dataset generated using formalin-fixed paraffin-embedded archival samples from two rare lung neuroendocrine tumor subtypes (namely, two atypical carcinoids, ACs, and two large-cell neuroendocrine carcinomas, LCNECs). Samples were subjected to a shotgun proteomics pipeline, comprising full-length protein extraction, SDS removal through spin columns, in solution trypsin digestion, long gradient liquid chromatography peptide separation and LTQ-Orbitrap mass spectrometry analysis. A total of 1260 and 2436 proteins were identified in the AC and LCNEC samples, respectively, with FDR <1%. MS data are available in the PeptideAtlas repository at http://www.peptideatlas.org/PASS/PASS00375.

Tanca, A., Addis, M. F., Pisanu, S., Abbondio, M., Pagnozzi, D., Eccher, A., Rindi, G., Cossu Rocca, P., Uzzau, S., Fanciulli, G., Atypical carcinoid and large cell neuroendocrine carcinoma of the lung: A proteomic dataset from formalin-fixed archival samples, <<DATA IN BRIEF>>, 2016; 7 (7): 529-531. [doi:10.1016/j.dib.2016.02.083] [http://hdl.handle.net/10807/94617]

Atypical carcinoid and large cell neuroendocrine carcinoma of the lung: A proteomic dataset from formalin-fixed archival samples

Rindi, Guido;
2016

Abstract

Here we present a dataset generated using formalin-fixed paraffin-embedded archival samples from two rare lung neuroendocrine tumor subtypes (namely, two atypical carcinoids, ACs, and two large-cell neuroendocrine carcinomas, LCNECs). Samples were subjected to a shotgun proteomics pipeline, comprising full-length protein extraction, SDS removal through spin columns, in solution trypsin digestion, long gradient liquid chromatography peptide separation and LTQ-Orbitrap mass spectrometry analysis. A total of 1260 and 2436 proteins were identified in the AC and LCNEC samples, respectively, with FDR <1%. MS data are available in the PeptideAtlas repository at http://www.peptideatlas.org/PASS/PASS00375.
Inglese
Tanca, A., Addis, M. F., Pisanu, S., Abbondio, M., Pagnozzi, D., Eccher, A., Rindi, G., Cossu Rocca, P., Uzzau, S., Fanciulli, G., Atypical carcinoid and large cell neuroendocrine carcinoma of the lung: A proteomic dataset from formalin-fixed archival samples, <<DATA IN BRIEF>>, 2016; 7 (7): 529-531. [doi:10.1016/j.dib.2016.02.083] [http://hdl.handle.net/10807/94617]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/94617
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 3
  • ???jsp.display-item.citation.isi??? 3
social impact