Plasma chitotriosidase activity (ChT) was previously proposed to quantify severity of sepsis. In a complex surgical case, with prolonged sepsis and consistently high ChT, we found that the least increased values occurred in stages of extreme illness, with profound hypocholesterolemia. ChT needs better characterization before becoming a reliable biomarker of septic evolution.
Chiarla, C., Giovannini, I., Antuzzi, D., Piras, A., Ardito, F., Giuliante, F., Clinical use of plasma chitotriosidase in severe sepsis, <<CURRENT MEDICAL RESEARCH AND OPINION>>, 2016; 32 (2): 273-276. [doi:10.1185/03007995.2015.1118370] [http://hdl.handle.net/10807/94261]
Clinical use of plasma chitotriosidase in severe sepsis
Chiarla, CarloPrimo
;Giovannini, Ivo
;Antuzzi, Daniela;Piras, Andrea;Ardito, FrancescoPenultimo
;Giuliante, FeliceUltimo
2016
Abstract
Plasma chitotriosidase activity (ChT) was previously proposed to quantify severity of sepsis. In a complex surgical case, with prolonged sepsis and consistently high ChT, we found that the least increased values occurred in stages of extreme illness, with profound hypocholesterolemia. ChT needs better characterization before becoming a reliable biomarker of septic evolution.
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