We followed 419 patients with a first, unprovoked, primarily or secondarily generalized tonic-clonic seizure, randomized to immediate antiepileptic treatment or to treatment only in the event of seizure recurrence. The probability of achieving a 2-year remission was 72 vs 57% at 3 months, 84 to 79% at 3 years, and 85 to 86% at 10 years (p NS). The probability of entering 5-year remission was 47 to 40, 58 to 58, and 64 to 64% (p NS). Early treatment does not affect the long-term prognosis of epilepsy.

Leone, M. A., Solari, A., Beghi, E., Mazza, S., Treatment of the first tonic-clonic seizure does not affect long-term remission of epilepsy., <<NEUROLOGY>>, 2006; (Dicembre): 2227-2229 [http://hdl.handle.net/10807/9341]

Treatment of the first tonic-clonic seizure does not affect long-term remission of epilepsy.

Mazza, Salvatore
2006

Abstract

We followed 419 patients with a first, unprovoked, primarily or secondarily generalized tonic-clonic seizure, randomized to immediate antiepileptic treatment or to treatment only in the event of seizure recurrence. The probability of achieving a 2-year remission was 72 vs 57% at 3 months, 84 to 79% at 3 years, and 85 to 86% at 10 years (p NS). The probability of entering 5-year remission was 47 to 40, 58 to 58, and 64 to 64% (p NS). Early treatment does not affect the long-term prognosis of epilepsy.
Inglese
Leone, M. A., Solari, A., Beghi, E., Mazza, S., Treatment of the first tonic-clonic seizure does not affect long-term remission of epilepsy., <<NEUROLOGY>>, 2006; (Dicembre): 2227-2229 [http://hdl.handle.net/10807/9341]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/9341
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