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EnglishExtramedullary relapse of multiple myeloma (MM) is uncommon. A 40-year-old woman with history of MM underwent PET/CT using 11 C-methionine (C-MET) after the detection of a vulvar lesion on MRI, biopsy proven to be extramedullary relapse of MM. The vulvar lesion was negative at the 18F-FDG PET/CT but showed high uptake of C-MET; focal uptake of both 18F-FDG and C-MET was shown within the muscles of the left leg, histologically confirmed as extramedullary relapse of MM. 18F-FDG PET/CT performed after chemotherapy showed no uptake in both sites, whereas posttreatment C-MET PET/CT showed persistence of residual uptake within the vulvar lesion.
Caldarella, C., Annunziata, S., Pagano, L., De Stefano, V., Rufini, V., Improved Detection of Minimal Residual Disease by 11C-Methionine PET/CT in a Young Patient with Unusual Extramedullary Presentation of Recurrent Multiple Myeloma, <<CLINICAL NUCLEAR MEDICINE>>, 2017; 42 (2): e130-e134. [doi:10.1097/RLU.0000000000001462] [http://hdl.handle.net/10807/93248]
| Autori: | |
| Titolo: | Improved Detection of Minimal Residual Disease by 11C-Methionine PET/CT in a Young Patient with Unusual Extramedullary Presentation of Recurrent Multiple Myeloma |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1097/RLU.0000000000001462 |
| URL: | http://journals.lww.com/nuclearmed/pages/default.aspx |
| Data di pubblicazione: | 2017 |
| Abstract: | Extramedullary relapse of multiple myeloma (MM) is uncommon. A 40-year-old woman with history of MM underwent PET/CT using 11 C-methionine (C-MET) after the detection of a vulvar lesion on MRI, biopsy proven to be extramedullary relapse of MM. The vulvar lesion was negative at the 18F-FDG PET/CT but showed high uptake of C-MET; focal uptake of both 18F-FDG and C-MET was shown within the muscles of the left leg, histologically confirmed as extramedullary relapse of MM. 18F-FDG PET/CT performed after chemotherapy showed no uptake in both sites, whereas posttreatment C-MET PET/CT showed persistence of residual uptake within the vulvar lesion. |
| Lingua: | Inglese |
| Rivista: | |
| Citazione: | Caldarella, C., Annunziata, S., Pagano, L., De Stefano, V., Rufini, V., Improved Detection of Minimal Residual Disease by 11C-Methionine PET/CT in a Young Patient with Unusual Extramedullary Presentation of Recurrent Multiple Myeloma, <<CLINICAL NUCLEAR MEDICINE>>, 2017; 42 (2): e130-e134. [doi:10.1097/RLU.0000000000001462] [http://hdl.handle.net/10807/93248] |
| Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |
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