Extramedullary relapse of multiple myeloma (MM) is uncommon. A 40-year-old woman with history of MM underwent PET/CT using 11 C-methionine (C-MET) after the detection of a vulvar lesion on MRI, biopsy proven to be extramedullary relapse of MM. The vulvar lesion was negative at the 18F-FDG PET/CT but showed high uptake of C-MET; focal uptake of both 18F-FDG and C-MET was shown within the muscles of the left leg, histologically confirmed as extramedullary relapse of MM. 18F-FDG PET/CT performed after chemotherapy showed no uptake in both sites, whereas posttreatment C-MET PET/CT showed persistence of residual uptake within the vulvar lesion.

Caldarella, C., Annunziata, S., Pagano, L., De Stefano, V., Rufini, V., Improved Detection of Minimal Residual Disease by 11C-Methionine PET/CT in a Young Patient with Unusual Extramedullary Presentation of Recurrent Multiple Myeloma, <<CLINICAL NUCLEAR MEDICINE>>, 2017; 42 (2): e130-e134. [doi:10.1097/RLU.0000000000001462] [http://hdl.handle.net/10807/93248]

Improved Detection of Minimal Residual Disease by 11C-Methionine PET/CT in a Young Patient with Unusual Extramedullary Presentation of Recurrent Multiple Myeloma

Caldarella, Carmelo
;
Annunziata, Salvatore
Secondo
;
Pagano, Livio;De Stefano, Valerio
Penultimo
;
Rufini, Vittoria
Ultimo
2017

Abstract

Extramedullary relapse of multiple myeloma (MM) is uncommon. A 40-year-old woman with history of MM underwent PET/CT using 11 C-methionine (C-MET) after the detection of a vulvar lesion on MRI, biopsy proven to be extramedullary relapse of MM. The vulvar lesion was negative at the 18F-FDG PET/CT but showed high uptake of C-MET; focal uptake of both 18F-FDG and C-MET was shown within the muscles of the left leg, histologically confirmed as extramedullary relapse of MM. 18F-FDG PET/CT performed after chemotherapy showed no uptake in both sites, whereas posttreatment C-MET PET/CT showed persistence of residual uptake within the vulvar lesion.
Inglese
Caldarella, C., Annunziata, S., Pagano, L., De Stefano, V., Rufini, V., Improved Detection of Minimal Residual Disease by 11C-Methionine PET/CT in a Young Patient with Unusual Extramedullary Presentation of Recurrent Multiple Myeloma, <<CLINICAL NUCLEAR MEDICINE>>, 2017; 42 (2): e130-e134. [doi:10.1097/RLU.0000000000001462] [http://hdl.handle.net/10807/93248]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/93248
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